FDG PET/CT in a Case of Lung Adenocarcinoma With Diffuse Cavitary Intrapulmonary Metastases

Abstract

We describe FDG PET/CT findings in a case of lung adenocarcinoma with diffuse cavitary intrapulmonary metastases at initial diagnosis. High-resolution CT of the chest showed the primary solid tumor in the right upper lobe and numerous cavitating metastases ranging from a few millimeters to 1 cm in the bilateral lungs. FDG PET/CT showed intense activity of the primary tumor, diffuse activity of the lung metastases, and hypermetabolic metastases in the mediastinal lymph nodes and bones. Familiarity with this atypical intrapulmonary metastatic pattern of lung cancer may be helpful for the diagnosis and differential diagnosis.

SMARCA4-Deficient Poorly Differentiated Adenocarcinoma of the Gallbladder

“…The patient dies 9 months after the histological diagnosis. SMARCA4-deficient tumors are characterized by low differentiation and high malignancy throughout the body 1–3 . Biliary tract adenocarcinoma with SMARCA4 deficiency is rare and limited in the literature 4 .…”

Bilateral Pulmonary Enteric Adenocarcinoma on FDG PET/CT

“…Hu et al 9 reported a case with multiple hypermetabolic soft tissue lesions in the lung, whose diagnosis was confirmed as intestinal-type adenocarcinoma, whereas our case manifested as diffuse intense FDG uptake in both lungs. Widespread abnormal FDG activity in both lungs can be seen due to many different etiologies 10–15 . Pulmonary enteric adenocarcinoma should be included in the differential diagnoses in interpreting similar FDG PET/CT findings.…”