Fe3O4/SiO2 Core/Shell Nanocubes: Novel Coating Approach with Tunable Silica Thickness and Enhancement in Stability and Biocompatibility

Abbas, Mohamed; Torati, Sri Ramulu; Lee, Chang‐Soo; Rinaldi, Carlos; Kim, CheolGi

doi:10.4172/2157-7439.1000244

Cited by 45 publications

(26 citation statements)

References 27 publications

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“…A small peak appeared at 1637 cm −1 that was related to the bending vibration of the water molecules absorbed onto the surface of the silica particles [ 35 ]. Characteristic peaks appeared at 1105 cm −1 , 792 cm −1 and 470 cm −1 that could be assigned to the asymmetrical stretching vibration of O–Si–O, the symmetrical stretching vibration of O–Si–O and the bending vibration of O–Si–O, respectively [ 36 , 37 , 38 , 39 ]. The peak of 1392 cm −1 related to the Si–O bond stretching and the band at 958 cm −1 indexed to the stretching vibrations of the silanol groups [ 35 ].…”

Section: Resultsmentioning

confidence: 99%

Facile Synthesis of Carboxymethyl Cellulose Coated Core/Shell SiO2@Cu Nanoparticles and Their Antifungal Activity against Phytophthora capsici

Hai

Cuong

Quyen³

et al. 2021

Polymers

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Cu nanoparticles are a potential material for creating novel alternative antimicrobial products due to their unique antibacterial/antifungal properties, stability, dispersion, low cost and abundance as well as being economical and ecofriendly. In this work, carboxymethyl cellulose coated core/shell SiO2@Cu nanoparticles (NPs) were synthesized by a simple and effective chemical reduction process. The initial SiO2 NPs, which were prepared from rice husk ash, were coated by a copper ultrathin film using hydrazine and carboxymethyl cellulose (CMC) as reducing agent and stable agent, respectively. The core/shell SiO2@Cu nanoparticles with an average size of ~19 nm were surrounded by CMC. The results indicated that the SiO2@Cu@CMC suspension was a homogenous morphology with a spherical shape, regular dispersion and good stability. Furthermore, the multicomponent SiO2@Cu@CMC NPs showed good antifungal activity against Phytophthora capsici (P. capsici). The novel Cu NPs-based multicomponent suspension is a key compound in the development of new fungicides for the control of the Phytophthora disease.

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Section: Resultsmentioning

confidence: 99%

Facile Synthesis of Carboxymethyl Cellulose Coated Core/Shell SiO2@Cu Nanoparticles and Their Antifungal Activity against Phytophthora capsici

Hai

Cuong

Quyen³

et al. 2021

Polymers

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“…After silica coating, the peak of Fe-O slightly shifted to 603 cm À1 . Furthermore, there is no more peak around 632 cm À1 observed, which the representative peak for Fe 2 O 3 denoting that the samples are purely magnetite Fe 3 O 4 [43]. The broad absorption band appeared around 1050 cm À1 in Fe 3 O 4 /SiO 2 core/shell nanoparticles is related to the asymmetric vibration of Si-O-Si bond.…”

Section: Characterization Of Fe 3 O 4 Nanoparticles and Mmsnsmentioning

confidence: 86%

Improved anticancer efficacy of epirubicin by magnetic mesoporous silica nanoparticles:in vitroandin vivostudies

Ansari

Jaafari

Bastami

et al. 2018

Artificial Cells, Nanomedicine, and Biotechnology

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The development of magnetic nanoparticles as delivery carriers to magnetically accumulate anticancer drug in cancer tissue has attracted immense interest. In the present study, magnetic mesoporous silica nanoparticles (MMSNs) with magnetite core and silica shell were synthesized. The obtained MMSNs were characterized by DLS, XRD, FT-IR, TEM and VSM in order to investigate the nanoparticle characteristics. With the focus on in vivo validation of such magnetic drug delivery systems, we selected epirubicin (EPI) as the drug. The anticancer properties of EPI-loaded MMSNs were evaluated in a C-26 colon carcinoma model. Alongside monitoring of drug in the tissues with animal imaging system, the tissue distribution was also determined quantitavely. The average size of MMSNs determined with TEM images was about 18.68 ± 2.31 nm. The cellular uptake test indicated that geometric mean fluorescence intensity (MFI) of cells treated with MMSN + EPI in presence of external magnetic field was increasing 27% compared with free EPI. In addition, treatment with drug-loaded MMSNs with the aid of external magnetic gradient had significantly higher inhibition efficacy towards tumor growth than the free EPI treated mice. The targeted drug delivery through external magnet-attraction using EPI-loaded MMSNs resulted in high tumor cell uptake, which leads to elimination of cancer cells effectively.

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“…Silica-coated magnetic nanoparticles are in general explored for applications, such as targeted drug delivery in the treatment of various diseases and transfection [122]. Silica-covered IONPs can be obtained through three different approaches: Stöber process [123,124], microemulsion synthesis [125,126], and aerosol pyrolysis [127]. Stöber process is the most used method consisting in formation of silica in situ as a result of hydrolysis and condensation of alkoxysilanes.…”

Section: Surface Coating Of Ionpsmentioning

confidence: 99%

“…The silica layer width was adjusted by varying the precursor concentration and reaction time. In this way, Abbas et al [126] prepared high quality superparamagnetic core-shell nanoparticles with great potential for medical application.…”

Section: Surface Coating Of Ionpsmentioning

confidence: 99%

Nanomaterials Developed by Processing Iron Coordination Compounds for Biomedical Application

Iacob¹,

Racleş²,

Dascălu³

et al. 2019

Journal of Nanomaterials

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The iron oxides, widespread in nature, are used in numerous applications in practice due to their well-known properties. These properties can be modified by size lowering at nanoscale. Some applications, such as biomedical, require a rigorous selection of nanoparticles by size, shape, and surface functionality. In other applications, such as catalysis or magnetism, the composition (generally mixed oxides) and morphology of the nanoparticles are of high importance. The preparation of iron oxide nanoparticles (IONPs) is a complex process whose control raises a number of issues. The first challenge is finding the optimal experimental conditions, which would lead to the preparation of monodisperse nanoparticles. Another issue is the selection or setting a reproducible and clean manufacturing process without a need of complex purification. Even though at the moment several methods for preparing IONPs are known, there are still concerns in the scientific world to further improve existing methods or create new protocols. Therefore, the establishment of optimal methods for preparing IONPs with predetermined structural, dimensional, and morphological characteristics is an important task of scientists. Most of the methods reported in literature for the preparation of IONPs use proper metal salts as precursors. Recently, the use of the organometallic and coordination compounds of iron as precursors for IONPs has emerged as an alternative for a better control of these. Here, achievements reported in the literature in this direction are reviewed and critically analysed in relation to the conventional method based on iron salts.

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Fe3O4/SiO2 Core/Shell Nanocubes: Novel Coating Approach with Tunable Silica Thickness and Enhancement in Stability and Biocompatibility

Cited by 45 publications

References 27 publications

Facile Synthesis of Carboxymethyl Cellulose Coated Core/Shell SiO2@Cu Nanoparticles and Their Antifungal Activity against Phytophthora capsici

Facile Synthesis of Carboxymethyl Cellulose Coated Core/Shell SiO2@Cu Nanoparticles and Their Antifungal Activity against Phytophthora capsici

Improved anticancer efficacy of epirubicin by magnetic mesoporous silica nanoparticles:in vitroandin vivostudies

Nanomaterials Developed by Processing Iron Coordination Compounds for Biomedical Application

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