Feasibility of sustained low efficiency dialysis in critically sick pediatric patients: A multicentric retrospective study

Abstract

SLED is a feasible method of providing renal replacement in critically ill pediatric patients.

Efficacy and safety of prolonged daily hemodialysis in critically ill children weighing less than 10 kg

“…Table 2 Comparison of complications in infants undergoing HD, CRRT, and children on SLED Lee et al 6 Sethi et al 7 Our study Santiago et al 11 Swadoski et al 8 Modality Two children have normal renal functions on follow-up.…”

“…6,7 The report by Lee et al had 14 children with a mean age of 14.9 AE 2.3 years and mean weight of 54.4 AE 23.3 kg. 7 Conventional HD has been used successfully in small infants including neonates for renal disease, hyperammonemia, or AKI. Their multicentric study had only one child less than 10 kg in weight who had tumor lysis syndrome without hemodynamic instability and received four sessions of SLED.…”

“…7 Conventional HD has been used successfully in small infants including neonates for renal disease, hyperammonemia, or AKI. 7 Hypotension is the most worrisome complication in extracorporeal therapies as it is potentially life and organ threatening. Hypotension was seen in 64%, but 96% of the sessions were completed without premature termination.…”

Working towards zero mortality from acute kidney injury in Sri Lanka

“…Dialysis modalities used in AKI are haemodialysis (HD) in haemodynamically stable patients and continuous renal replacement therapy (CRRT) and slow low-efficiency dialysis (SLED) for haemodynamically unstable patients 8 . As most patients with infections with AKI are haemodynamically unstable, CRRT has been the preferred mode of dialysis.…”

“…It is further increased if the interventions are delayed, principally due to fluid overload and electrolyte imbalances leading to multi organ failure 8 . In a developing country like Sri Lanka facilities to treat AKI are available only in few major centres in the country.…”