“…The underlying clinical conditions include short gut syndrome, severe gut dysfunction, mesenteric vascular insufficiency, bowel obstruction, GI bleeding, severe diarrhea, large volume fistulas, sepsis, severe burns, and trauma associated with continuous hemodynamic instability and with severe fulminant acute and chronic pancreatitis. In many of these patient subgroups, TPN is lifesaving (Dudrick 2007;Latifi and Uraneus 2013).…”