Plants are regarded as the richest research for many potential drugs. Medicinal plants have been used for the treatment of various diseases since ancient time. The bioactive compounds like different phytochemicals are extracted from various parts of the medicinal plants, as they serve as traditional herbal drugs. These drugs are well recognized in modern medication system due to natural products, much safer, effective in curing various diseases and it have less side effects. The secondary metabolite like tannine, saponin, flavonoids, alkaloids and phenolic compounds are widely used in pharmaceuticals. Therefore, some plants are usage as medicine for curing different diseases. Piper cubeba (Kabab Chini) is tropical medicinal plants which are common in Indonesia and different parts of the world. It has been reported that Piper cubeba is potential medicinal plant which has various phytochemicals and its uses in antimicrobial, anti-inflammatory, antibacterial, antioxidant, anti-cancerous, hepatoprotective, nephroprotective and antileishmanial activity. Thus, the aim of this review of literatures is to describe the phytochemicals and pharmaceutical attributes of Piper cubeba, which possess a broad range in biological activities.