Fetal blood sampling in twin pregnancies

Abstract

ABSTRACT

Comparisons of outcomes after cordocentesis at mid‐pregnancy between singleton and twin pregnancies

“…The data from previous studies and ours are summarized in Table 3. Compared with previous studies (Cox et al , 1987; Antsaklis et al , 2003), fetal loss within 2 weeks of the procedure in our study occurred at the lowest rate (1.1%), whereas the success rate of fetal blood sampling was comparable. However, several aspects of the techniques do not allow proper comparison of the results.…”

“…The time frames of database collection, especially in the study by Cox et al (1987), could have affected the quality of the ultrasound imaging. In the largest study reported by Antsaklis et al (2003), the fetal loss rate was 8.2% but the series also included fetal blood samplings via fetoscopy, which is a more invasive technique of fetal blood sampling.…”

“…Many studies on cordocentesis in singleton pregnancies have been published (Kanokpongsukdi et al , 1985; Rudigoz et al , 1990; Bell and Weiner, 1993; Wax and Blakemore, 1993; Megerian and Ludomirsky, 1994; Pardi et al , 1994; Wilson et al , 1994; Bernaschek et al , 1995; Donner et al , 1995; Tongsong et al , 2000; Tongsong et al , 2001). However, studies about this procedure in twin pregnancies have been reported in only a very limited number, and at various gestational ages (Cox et al , 1987; Okamura et al , 1994; Antsaklis et al , 2003; Weisz and Rodeck, 2005; Tongprasert et al , 2007), including one from our center (Tongprasert et al , 2007). However, all of the previous studies are case series with descriptive analysis and included only a small number of cases.…”

Monochorionic Twin Pregnancy— Potential Risks and Perinatal Outcomes

“…Mortality rates are high, reaching 80 to 100% in untreated disorders. There is also high occurrence of miscarriage, premature rupture of membranes, preterm delivery and spontaneous death of one or both siblings [79].…”