Fever and temporal headache in a 70-year-old male with presumed large vessels vasculitis

Vettas, Christos; Dimosiari, Athina; Kydona, C.; Pyrpasopoulou, Athina; Avdelidou, Eugenia; Roilidis, Emmanouil; Garyfallos, Alexandros; Dimitroulas, Theodoros

doi:10.31138/mjr.31.2.220

Cited by 3 publications

(1 citation statement)

References 11 publications

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“…Other possible manifestations include seizures, cranial nerve palsies, impaired consciousness, and brainstem, cerebellum, and extrapyramidal system involvement. LM infections can affect the meninges and brain parenchyma, resulting in meningitis, meningoencephalitis, and in a minority of cases, rhombencephalitis or brain abscesses ( 3 , 37 – 39 ). The main clinical features observed in the present study were fever (20/20, 100%), vomiting (15/20, 75%), and altered state of consciousness (19/20, 95%).…”

Section: Discussionmentioning

confidence: 99%

Clinical characteristics and prognosis of pediatric Listeria monocytogenes meningitis based on 10-year data from a large children’s hospital in China

Xia,

Zhang,

Zheng

et al. 2024

Microbiol Spectr

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This study aims to summarize the clinical characteristics and prognosis of Listeria monocytogenes (LM) meningitis in children in Chongqing, China. A retrospective analysis of the clinical data and follow-up results of 20 LM meningitis patients admitted to the Children’s Hospital of Chongqing Medical University (CHCMU) from January 2012 to December 2022 was performed. The LM meningitis incidence rate was between 0 and 14.3 per 100,000 persons. The median age at onset was 8.98 months. There were five neonate cases, which all had perinatal abnormalities. Seven non-neonatal cases (7/15, 46.7%) had a documented history of contaminated food intake. One case had primary immunodeficiency. The most common symptoms were fever (20/20), altered consciousness (19/20), and vomiting (15/20). Seven cases had seizures, eight cases had cranial nerve involvement, eight cases had positive Babinski sign, and 10 cases had positive meningeal signs. The most common complications were hyponatremia (6/20), hypokalemia (6/20), respiratory failure (5/20), subdural effusion (3/20), and hydrocephalus (2/20). Treatment primarily involved monotherapy or combination therapy with meropenem (15/20) and ampicillin (10/20). Fifteen cases were treated with monotherapy or combination therapy using vancomycin. Twelve cases were successfully followed up from 10 months to 9 years and 6 months, and all had favorable long-term outcomes. LM meningitis incidence in children is low and with nonspecific clinical manifestations. Strengthening food hygiene and safety education, and avoiding infections during pregnancy are important to prevent LM infection in neonates and high-risk individuals. Meropenem and ampicillin are the preferred treatments. Early diagnosis and treatment can improve prognosis. IMPORTANCE The incidence of LM meningitis is extremely low, and there is currently no standardized treatment. We conducted a retrospective analysis of ten years of data from CHCMU regarding diagnosed LM meningitis cases, aiming to provide clinical evidence for the diagnosis and treatment.

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Section: Discussionmentioning

confidence: 99%

Clinical characteristics and prognosis of pediatric Listeria monocytogenes meningitis based on 10-year data from a large children’s hospital in China

Xia,

Zhang,

Zheng

et al. 2024

Microbiol Spectr

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Cranial giant cell arteritis mimickers: A masquerade to unveil

Evangelatos

Grivas

Παππά

et al. 2022

Autoimmunity Reviews

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Imaging modalities in neurolisteriosis: a literature review

Zawadzki,

Rogalska,

Pałdyna

et al. 2024

Pol J Radiol

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Listeriosis caused by Listeria monocytogenes due to its ability to withstand harsh conditions and form biofilms on post-processed food poses a serious public health issue. It typically manifests itself with fever and gastrointestinal symptoms, but it can escalate with life-threatening conditions, especially in immunocompromised patients, the elderly, oncologically sick, and even pregnant women. The diagnosis is based on blood and cerebrospinal fluid culture growth, but it presents significant challenges due to deceptive findings and low positivity rates, the golden standard includes molecular diagnostic tests such as real-time PCR and metagenomic next-generation sequencing, which offer higher sensitivity and rapid detection. Radiological imaging, particularly magnetic resonance imaging, can play a crucial role in diagnosis of central nervous system (CNS) invasion by L. monocytogenes, enabling the detection of characteristic CNS lesions. The aim of the paper was to sum up the imaging features of L. monocytogenes CNS invasions in conventional imaging techniques, which can potentially speed up the diagnostic workflow for patients presenting with neurological symptoms associated with L. monocytogenes infection, particularly when conventional tests yield inconclusive results.

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Fever and temporal headache in a 70-year-old male with presumed large vessels vasculitis

Cited by 3 publications

References 11 publications

Clinical characteristics and prognosis of pediatric Listeria monocytogenes meningitis based on 10-year data from a large children’s hospital in China

Clinical characteristics and prognosis of pediatric Listeria monocytogenes meningitis based on 10-year data from a large children’s hospital in China

Cranial giant cell arteritis mimickers: A masquerade to unveil

Imaging modalities in neurolisteriosis: a literature review

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