Fever Management in Intensive Care Patients with Infections

Young, Paul; Saxena, Manoj

doi:10.1007/978-3-319-03746-2_1

Cited by 6 publications

(9 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These pyrogenic cytokines acts on organum vasculosum area of the brain known as laminae terminalis leading to activation of the enzyme cyclo-oxygenase-2 (COX-2) that results in release of prostaglandin E 2 (PGE 2 ), which binds to receptors in the hypothalamus leading to an increase in heat production and a decrease in heat loss until the temperature in the hypothalamus reaches a elevated set-point 13 . TABLE 1: ALLOPATHIC TREATMENT OF PAIN For mild pain For moderate pain For severe pain Non-narcotic analgesic or NSAIDs like Aspirin 14 , paracetamol 15 , ibuprofen 16 , acetaminophen 17 , diclofenac 18 , meloxicam 19 are used to treat mild pain if the pain is unable to recover then narcotic drugs is recommended.…”

Section: Pathophysiology Of Fevermentioning

confidence: 99%

Untitled

2015

IJPSR

View full text Add to dashboard Cite

Pain is a subjective, multidimensional and unpleasant experience allied with actual or potential tissue damage comprising sensory, affective and cognitive components. Pain signals interpretation is a complex process that entails excitation of peripheral nerves and further excitation of nociceptive inputs. Painkiller is member of diverse group of drugs used to relieve pain and to achieve analgesia. Fever is recognized as physiological response which is triggered by infectious stimuli or aseptic stimuli. Elevation in body temperature occur when concentrations of prostaglandin-E2 (PGE2) increases within certain areas of the brain. These elevations alter the firing rate of neurons that control thermoregulation in the hypothalamus. It is commonly suppressed with antipyretic medications. Several traditional medicinal systems are available for the treatment of pain & fever like ayurveda, unani, chinese, homeopathic, physiotherapy & non-pharmacological procedures etc. Pain & fever treatment in allopathic system are frequently used but has many adverse effects like renal & liver dysfunction, ulceration, sedation, dizziness, nausea, vomiting, constipation, physical dependence, tolerance and respiratory depression etc. This compilation addresses the different medicinal systems and therapies used for the treatment of pain and fever

show abstract

Section: Pathophysiology Of Fevermentioning

confidence: 99%

Untitled

2015

IJPSR

View full text Add to dashboard Cite

show abstract

“…It refers to a defensive response of the body against pyrogenic agents released as part of an inflammatory process, causing increased immune response and protection of the human body against infectious agents (1) . Due to the high risk of infection associated with invasive procedures, immunosuppression, pathological conditions and environmental risks present in intensive care units (ICU), fevers occur in more than one-third of critical patients (2) . It is therefore a frequent event in this type of unit, with over 50% of individuals admitted to ICU presenting fevers due to infectious or non-infectious causes (1,3) .…”

Section: Introductionmentioning

confidence: 99%

“…It is therefore a frequent event in this type of unit, with over 50% of individuals admitted to ICU presenting fevers due to infectious or non-infectious causes (1,3) . Literature indicates that due to hemodynamic instability that critical patients may present, fever is a symptom that should be eliminated or reduced with drug treatment, and should also be associated or not to physical methods with patients presenting this profile (2,4) . Therefore, the care of patients with fever demands a set of appropriate, specific and related care based on scientific evidence, however, little is known about the best provision of care.…”

Section: Introductionmentioning

confidence: 99%

Physical methods for the treatment of fever in critically ill patients: a randomized controlled trial

Salgado

Silva

et al. 2016

Rev. esc. enferm. USP

View full text Add to dashboard Cite

Objective:To evaluate the effects of physical methods of reducing body temperature (ice pack and warm compression) in critically ill patients with fever. Method: A randomized clinical trial involving 102 adult patients with tympanic temperature ≥ 38.3°C of an infectious focus, and randomized into three groups: Intervention I -ice pack associated with antipyretic; Intervention II -warm compress associated with antipyretic; and Control -antipyretic. Tympanic temperature was measured at 15 minute intervals for 3 hours. The effect of the interventions was evaluated through the Mann-Whitney test and Survival Analysis. "Effect size" calculation was carried out. Results: Patients in the intervention groups I and II presented greater reduction in body temperature. The group of patients receiving intervention I presented tympanic temperature below 38.3°C at 45 minutes of monitoring, while the value for control group was lower than 38.3°C starting at 60 minutes, and those who received intervention II had values lower than 38.3°C at 75 minutes of monitoring. Conclusion: No statistically significant difference was found between the interventions, but with the intervention group I patients showed greater reduction in tympanic temperature compared to the other groups.

show abstract

“…Even in sepsis, to which significantly more resources are devoted, it isn't clear if normothermia or mild hyperthermia is better. 30 There is little published work on the effects of cooling in non-septic patients. Observational data suggest that the mortality is 13-fold higher at a temperature of 39.5 C compared with normothermia; 10 whether artificially lowering the temperature has the same effect isn't known.…”

mentioning

confidence: 99%

“…Then again, they may not be effective in sepsis, either. 30 Medicine progresses. Ice packs in the groins and axillae, surface cooling and body cavity cooling became available but achieving a target temperature, and controlling the speed of change, are difficult.…”

mentioning

confidence: 99%