Fiber-coupler-based microfluidic system for trapping of DNA biomolecules

Wu, Jixuan; Wang, Qian; Song, Binbin; Liu, Bo; Zhang, Hao; Zhang, Cheng; Duan, Shaoxiang; Bai, Hua

doi:10.1007/s11801-019-9147-5

Cited by 3 publications

(3 citation statements)

References 27 publications

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“…Optical fiber couplers based on two SMFs couplings do not have natural microfluidic channels, so they need to be integrated in microfluidic chips, capillaries or T‐tube‐assisted fluid devices for real‐time optofluidic biochemical detection. [ 84,246 ]…”

Section: Optical Fiber Optofluidic Bio‐chemical Sensors Based On Opti...mentioning

confidence: 99%

“…In the light of the preparation methods, optical fiber couplers based on two SMFs couplings can be divided into four types: Parallel structure microfiber coupler, [ 247–250 ] double helix microfiber coupler, [251] twisted microfiber coupler [252] and loop fiber coupler, [ 246,253,254 ] as shown in Figure . The first three optical fiber couplers belong to the transmissive structure, and the last one belongs to the reflective structure.…”

Section: Optical Fiber Optofluidic Bio‐chemical Sensors Based On Opti...mentioning

confidence: 99%

“…As a result, RI sensitivities of the OMCs could be improved by several orders of magnitude with the Vernier effect. Compared with the transmissive structures, the reflective loop fiber couplers have the advantages of compact structure, low transmission loss, and small free spectral range, and have been utilized for the detection of liquid RI, [253] chloride ion concentration, [254] and DNA biomolecules [246] …”

Section: Optical Fiber Optofluidic Bio‐chemical Sensors Based On Opti...mentioning

confidence: 99%

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Optical Fiber Optofluidic Bio‐Chemical Sensors: A Review

Zhang

Zhou

et al. 2021

Laser & Photonics Reviews

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Optofluidic, as an emerging technology that combines photons and microfluidics, has become a powerful, intelligent, and universal sensing platform in the field of bio-chemical sensing. Optical fiber optofluidic (OFOF), as a branch of optofluidic technology, has stimulated a host of remarkable achievements in the field of bio-chemical sensing due to its superiority of compact structure, immunity to electromagnetic interference, low sample consumption, high sensitivity, and real-time dynamic response. In this paper, an overview of OFOF bio-chemical sensors is presented. The OFOF system architectures are introduced and some advanced functional materials and coating technologies that can be utilized in the OFOF sensing platform to achieve high-performance biochemical sensing are summarized. Research progress and current status of OFOF bio-chemical sensors based on various sensing mechanisms are summarized and analyzed, with emphases on their sensing principles, sensing structures, sensing applications, advantages, and disadvantages. Lastly, the existing challenges and future development trends of OFOF biochemical sensors are briefly discussed.

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Section: Optical Fiber Optofluidic Bio‐chemical Sensors Based On Opti...mentioning

confidence: 99%