Abstract:Recent studies suggest that the cross-sectional relationship between reading skills and white matter microstructure, as indexed by fractional anisotropy, is not as robust as previously thought. Fixel-based analyses yield fiber-specific micro- and macrostructural measures, overcoming several shortcomings of traditional DTI approaches. We ran a whole-brain analysis investigating whether fixel-derived metrics related to single-word reading skills in a large, open, quality-controlled data set of 983 children and a… Show more
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