2023
DOI: 10.1007/978-3-031-21410-3_12
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Fibrinogen, Coagulation, and Ageing

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Cited by 4 publications
(2 citation statements)
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“…Being a signi cant clotting factor, brinogen plays an essential role in the cascade of clotting reactions, and other clotting factors are now recognized for their crucial involvement in the acute-phase response to tissue injury (16). Research indicates that elevated levels of brinogen are typically associated with an increased risk of thrombus formation and in ammation, impacting a patient's postoperative recovery and outcome, often resulting in extended hospitalization (17). In ammation plays a crucial role in regulating the activities of the coagulation and brinolysis systems, as it has been extensively acknowledged in literature (18).…”
Section: Discussionmentioning
confidence: 99%
“…Being a signi cant clotting factor, brinogen plays an essential role in the cascade of clotting reactions, and other clotting factors are now recognized for their crucial involvement in the acute-phase response to tissue injury (16). Research indicates that elevated levels of brinogen are typically associated with an increased risk of thrombus formation and in ammation, impacting a patient's postoperative recovery and outcome, often resulting in extended hospitalization (17). In ammation plays a crucial role in regulating the activities of the coagulation and brinolysis systems, as it has been extensively acknowledged in literature (18).…”
Section: Discussionmentioning
confidence: 99%
“…The risk and unwanted effects depend on the amount administered and the time of administration: studies have shown that if they are high and are administered for a short time they can cause serious effects [140]. In recent years, the administration methods have changed and new molecules have been discovered that involve a lower risk (reduced by 75%) regarding coagulation and metabolic alterations [5,141].…”
Section: Managementmentioning
confidence: 99%