Fibrous lesions of the gingiva: A histopathologic analysis of 204 cases

Abstract

Two hundred four cases of fibrous lesions of the gingiva were studied histologically for the presence of calcified tissue, the nature of the connective tissue, the type of keratinization, and the degree of epithelial thickness. Initially these lesions were subcategorized into four specific entities, namely fibrous epulis, fibroepithelial polyp, calcifying fibroblastic granuloma, and ossifying fibrous epulis. It was found that 46.5% of the lesions contained calcifications. The connective tissue was represented predominantly by either the collagenous type (50.5%) or the mixed (cellular and collagenous) type (44.6%). It was also found that 36% of the lesions were ulcerated, and, of these, 79.5% were associated with the cellular type of connective tissue and calcifications. In an attempt to subcategorize the fibrous lesions into specific entities, it was found that 32 cases (15.7%) had mixed features. This fact supports the suggestion that these lesions are stages in the spectrum of a single disease process and should collectively be termed fibroblastic gingival lesions. However, it is also suggested that the two terms, namely peripheral fibroma and fibrous epulis with and without ossification, should be retained whereas the usage of other terminologies should be avoided.

Accumulation of cells containing factor XIII subunit a around the foci of intense fibrosis in human epulides

“…Despite an extremely high incidence of epulis, little attention has been directed toward them, since the prognosis after eradication of irritation and complete surgical removal of them is usually favourable. On the basis of their histological characteristics, epulides are subdivided into different groups (Btfchner et al, 1977), and approximately 64.5-95% of these lesions are classified as fibrous epulis (collagenous), granulomatous epulis (cellular or vascular) or mixed (cellular and collagenous) epulis (Lee, 1986;Macleod & Soames, 1987;Zain & Fei, 1990). These different types of epulides are intimately related to one another, since they represent varying stages of a spectrum of one and the same disease process, i.e.…”

“…These different types of epulides are intimately related to one another, since they represent varying stages of a spectrum of one and the same disease process, i.e. stages in the formation of a reactive fibrous lesion, as a consequence of chronic irritation (Macleod & Soames, 1987;Zain & Fei, 1990). Initially, the profuse formation of granulation tissue can be visualized (granulomatous epulis); however, with aging, fibrotic processes become more and more dominant (mixed type epulis), and eventually the lesion matures into fibrous epulis.…”

Reactive Hyperplastic Lesions of the Gingiva: A Retrospective Study of 260 Cases

“…It has been referred to by various names, including 'peripheral fibroma with calcification' and 'calcifying fibroblastic granuloma'. 19,20 POF resembles clinically and histopathologically to pyogenic granuloma, hence some consider POF to develop secondary to fibrosis of granulation tissue. 21 POF more commonly occurs in females and in the second decade, hence the role of hormones has also been questioned.…”

Peri̇feri̇al Odontojeni̇k Fi̇broma: Nadi̇r Bi̇r Olgu

“…10 Klinik görünüşleri benzer olabilmesine rağmen ossifying fibrom POF"un aksine gingivanın reaktif fibröz lezyonudur. 11 Lin ve ark. 15 yaptıkları çalışmada örneklerin tamamında epitel ile birlikte dentin-sement benzeri kalsifikasyon göstermişlerdir.…”