Fibula free flap pedicle ossification: Experience of two centres and a review of the literature

Baserga, C.; Massarelli, Olindo; Bolzoni, Alessandro; Rossi, Diego; Beltramini, Giada Anna; Baj, A.; Giannì, Aldo Bruno

doi:10.1016/j.jcms.2018.06.019

Cited by 17 publications

(23 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Vascular pedicle ossification refers to graft pedicle experiencing calcification which could be identified both on CT scanning and with naked eyes under operation. Though it has a low incidence (4.4%) [79] and only reported as sporadic cases for 12 times [80][81][82][83], it causes hard swelling, trismus, and severe pain which absolutely indicate a surgical intervention. Interestingly, all these cases are documented in mandibular reconstruction and no cases in other reconstruction like spine or extremities Potential causes of this complication include bony contact, stress, infection and steroid-use.…”

Section: Mandibular Reconstructionmentioning

confidence: 99%

Complication of osteo reconstruction by utilizing free vascularized fibular bone graft

Zhou

et al. 2020

BMC Surg

View full text Add to dashboard Cite

The success of free vascularized fibular bone graft (FVFBG) has accelerated the osteo reconstruction which results from trauma, resection of a tumor or an infectious bone segment, or correction of congenital deformity. But the complication behind should not be overlooked. The failure could necessitate a second surgery, which prolong the rehabilitation period and produce further health cost. Worst, the patients may suffer a permanent impaired ankle function, or a sustained morpho-functional loss on reconstructive area which are hard to save. To provide an overview of the complication related to reconstruction by FVFBG, a narrative review is conducted to identify the complications including their types and rates, the contributing factors, the approaches to measure and the techniques to avoid. Methodologically, by quick research on Pubmed and abstract reading of reviews, we characterize five reconstructive areas where FVFBG were most frequently applied: extremities, mandible, spine, osteonecrosis of femoral head, and penile. Following, the complications on different reconstructive areas are retrieved, studied and presented in five (or more specifically, six) separate sections. By the way, meaningful difference between FVFBG and other bone flap was presented in a few words if necessary. Donor-site morbidities were studied and summarized as a whole. In these literatures, the evidences documented on limb and mandibular reconstruction have the fullest detail, followed by the spine and lastly the penile. In conclusion, FVFBG, though a mature technique, needs further deep and comprehensive study and maybe device-based assistance to achieve better reconstructive effect and minimize donor-site damage.

show abstract

Section: Mandibular Reconstructionmentioning

confidence: 99%

Complication of osteo reconstruction by utilizing free vascularized fibular bone graft

Zhou

et al. 2020

BMC Surg

View full text Add to dashboard Cite

show abstract

“…2 Some studies describe that the hormonal microenvironment (eg, high concentrations of estrogen and doses of dexamethasone) has been shown to increase osteogenic capacity. 5 However, this is disputed by some reports demonstrating a higher incidence of ossification in men or no statistical difference among sexes. 6,8 Conservative therapy includes oral physiotherapy for 6 months after surgery.…”

Section: Clinical Challenge | Radiologymentioning

confidence: 99%

“…8 Stretchingoftheperiosteumduringspeechandmastication may be a key stimulus for osteogenesis. 5 In a rabbit model, costal periosteum has been shown to regenerate bony defects in the tibia within 6 weeks. 9 Other theories include fracture repair, blood flow, local mechanics, and hormonal influence.…”

Section: Clinical Challenge | Radiologymentioning

confidence: 99%

Chronic Neck Pain After Oromandibular Reconstruction

Dumberger

Mady

Cannady

2021

JAMA Otolaryngol Head Neck Surg

View full text Add to dashboard Cite

“…The designated areas (white rectangle) showed the initial formation of fibrous tissue, which was an extracellular matrix. Ossification is a prolonged process and other techniques can be applied to better study the ossification [59,60].…”

Section: In Vivo Studymentioning

confidence: 99%

Surface Modification of 316L SS Implants by Applying Bioglass/Gelatin/Polycaprolactone Composite Coatings for Biomedical Applications

et al. 2020

View full text Add to dashboard Cite

In this study, various composites of bioglass/gelatin/polycaprolactone (BG/GE/PCL) were produced and coated on the surface of 316L stainless steel (SS) to improve its bioactivity. X-ray diffractometry (XRD), scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDS) were utilized to characterize the specimens. The results showed that bioglass particles were distributed uniformly in the coating. By increasing the wt.% of bioglass in the nanocomposite coatings, the surface roughness and adhesion strength increased. The corrosion behavior of GE/PCL (PCL-10 wt.% gelatin coated on 316L SS) and 3BG/GE/PCL (GE/PCL including 3 wt.% bioglass coated on 316L SS) samples were studied in PBS solution. The results demonstrated that 3BG/GE/PCL sample improved the corrosion resistance drastically compared to the GE/PCL specimen. In vitro bioactivity of samples was examined after soaking the specimens for 7, 14 and 28 days in simulated body fluid (SBF). The results showed a significant apatite formation on the surface of 3BG/GE/PCL samples. The cell viability evaluation was performed using 3- (4, 5-dimethylthiazol-2-yl)-2,5 diphenyltetrazoliumbromide (MTT) tests which confirmed the enhanced cell viability on the surface of 3BG/GE/PCL samples. The in vivo behavior of specimens illustrated no toxicity and inflammatory response and was in a good agreement with the results obtained from the in vitro test.

show abstract

Fibula free flap pedicle ossification: Experience of two centres and a review of the literature

Cited by 17 publications

References 22 publications

Complication of osteo reconstruction by utilizing free vascularized fibular bone graft

Complication of osteo reconstruction by utilizing free vascularized fibular bone graft

Chronic Neck Pain After Oromandibular Reconstruction

Surface Modification of 316L SS Implants by Applying Bioglass/Gelatin/Polycaprolactone Composite Coatings for Biomedical Applications

Contact Info

Product

Resources

About