Ficus species (Ficus auriculata Lour., Ficus benghalensis L., Ficus carica L., Ficus religiosa L., Ficus semicordata Buch.Ham. ex Sm).

Adhikari, Yagya P.; Bhandari, Prabin; Adhikari, Dhaka M.; Kunwar, Ripu M

doi:10.1016/b978-0-323-85591-4.00030-1

Cited by 3 publications

(1 citation statement)

References 41 publications

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“…One of the plants that have antidiabetic activity is the fig or fig fruit, but what is often used from this plant is the leaves to lower blood glucose in the body (WU et al, 2022). Plants are often used directly by the people of Bone, especially in the Lapri area, because they are alternative medicines for the treatment of Diabetes, which have fewer side effects than chemical drugs (Adhikari et al, 2023)…”

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confidence: 99%

Effectiveness of Fig Leaf Extract (Ficus Carica L.) in Lowering Blood Glucose in Mice (Mus Musculus)

Aisyah,

TR Dewi,

Jumain

2023

ihj

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Fig leaves (Ficus carica L.) is a plant that has antidiabetic properties, because fig leaves contain alkaloid compounds, flavonoids, tannins, polyphenols, saponins, terpenoids, and steroids. This study aims to determine the extract of fig leaves (Ficus carica L.) in lowering blood glucose in mice (Mus musculus). Extraction is carried out by maceration with 96% ethanol solvent, then evaporated using Rotavapor. This study used alloxane as a diabetes inducer, the dose of fig leaf extract tested was 5%, 10% and 15% given orally. Observations were made on day 3 and day 7. As a positive control used Glibenclamide and Na. CMC 1% w/v as a negative control. The results showed an average percent reduction in blood glucose levels for negative controls by 18.6%, for 5% extracts by 29.1%, for 10% extracts by 46.6%, for 15% extracts by 83.9% and for positive controls by 45.8%. The results of research have been obtained that the administration of Fig Leaf extract (Ficus carica L.) is proven to reduce blood glucose levels in mice (Mus musculus) induced by alloxane at concentrations of 5%, 10%, 15%. In the One-way ANOVA test, it shows a significant value (p < 0.05) showing a significant difference in each contract. It can be concluded that fig leaves can be a potential alternative treatment for diabetes mellitus with the right concentration can be an effective and natural treatment option.

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Section: Introductionmentioning

confidence: 99%

Effectiveness of Fig Leaf Extract (Ficus Carica L.) in Lowering Blood Glucose in Mice (Mus Musculus)

Aisyah,

TR Dewi,

Jumain

2023

ihj

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Himalayan fruit and circular economy: nutraceutical potential, traditional uses, challenges and opportunities

Ritika,

Bora,

Ismail

et al. 2024

Food Prod Process and Nutr

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The Himalayas, globally acknowledged as one of the four biodiversity hotspots, underscore their ecological significance, boasting abundant flora and fauna. Among these, a diverse array of wild fruits such as Aegle marmelos, Artocarpus lakoocha, Baccaurea spp., Carissa spp., and others provide essential nutrition for local populations. These fruits, rich in bioactive compounds, offer nutraceutical potential, contributing to health aspects like antidiabetic, anti-inflammatory, and anticancer properties. The integration of Himalayan wild fruits into circular practices supports sustainable livelihoods. The responsible harvesting, efficient processing, and value addition of these fruits align with circular principles, striking a balance between conservation and progress. Technologies such as anaerobic digestion, waste-to-energy conversion, and composting can harness waste generated during cultivation and processing, contributing to a circular economy and rural Himalayan community development. Preserving, accessing, and commercializing underutilized fruits can significantly enhance economic prosperity and the quality of life for inhabitants. However, integrating these fruits into agriculture faces multifaceted challenges, spanning social, economic, environmental, agronomic, and political dimensions. Addressing these challenges is crucial for sustainable development, aiming to eradicate poverty, malnutrition, and hidden hunger. Moreover, addressing these challenges is not only vital for sustainable development in the Himalayan region but also for mitigating carbon footprints and tackling issues like poverty, malnutrition, hidden hunger, and climate change. The exploration of these concepts within the Himalayan context holds immense promise for sustainable development and ecological conservation. Graphical Abstract

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Comparative analysis of antioxidant activities of Vitex negundo and Ficus carica leaf extracts

Anjali¹,

Joshi

2023

J Exp Bio & Ag Sci

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Humans have been dependent on nature for various vital supplies and resources for a long time. Most biotechnological and pharmacological industries use chemicals and active compounds to treat diseases or make medications isolated from natural resources. A variety of plants have been explored for research of which Vitex negundo and Ficus carica are also examples as they are strong candidates for their potential antioxidant properties. In the current research, the anti-oxidant activities of V. negundo and F. carica leaf extracts were evaluated. The antioxidant activities of selected plants were analyzed using DPPH and FRAP assay. The results obtained from the DPPH assay indicated that methanolic extracts of V. negundo showed the highest inhibition of 90.07±1.17 percent at 1000 µl with IC50 value of 415.98 µg/ml followed by ethyl acetate and chloroform extracts (64.05±0.89 and 54.39±0.99 percent, respectively) with IC50 value of 751.96 µg/ml and 896.55 µg/ml when compared to F. carica extracts which showed highest inhibition of 75.75±1.08 percent at 1000 µl with IC50 value of 475 µg/ml followed by ethyl acetate and chloroform extracts (51.94±0.79 and 44.21±0.60 percent respectively) with IC50 value of 967.51 µg/ml and 1092.48 µg/ml. On comparing both plants, FRAP results indicated that methanol extracts of V. negundo showed the highest FRAP value (1042.1±0.98 µM) followed by ethyl acetate and chloroform extracts, which shows 996.6±1.25 µM and 949.6±1.63 µM at 1000 µl whereas F. carica showed highest FRAP value (995.6±1.35µM) followed by ethyl acetate and chloroform extracts, which shows 987.6±1.05µM and 447.6±1.01µM at 1000 µl. The results of the study can be concluded that among the tested extracts, the best antioxidant potential was exhibited with V. negundo leaf extracts, especially in methanol extracts.

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Ficus species (Ficus auriculata Lour., Ficus benghalensis L., Ficus carica L., Ficus religiosa L., Ficus semicordata Buch.Ham. ex Sm).

Cited by 3 publications

References 41 publications

Effectiveness of Fig Leaf Extract (Ficus Carica L.) in Lowering Blood Glucose in Mice (Mus Musculus)

Effectiveness of Fig Leaf Extract (Ficus Carica L.) in Lowering Blood Glucose in Mice (Mus Musculus)

Himalayan fruit and circular economy: nutraceutical potential, traditional uses, challenges and opportunities

Comparative analysis of antioxidant activities of Vitex negundo and Ficus carica leaf extracts

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