Figure S1-S6,Table S1,Supplementary Methods from Epigenetic Profiling Identifies LIF as a Super-enhancer-Controlled Regulator of Stem Cell–like Properties in Osteosarcoma

Abstract

<p>Supplementary Figure 1. Super-enhancers (SEs) in osteosarcoma cells. Related to Figure 1. Supplementary Figure 2. LIF promotes epithelial-mesenchymal transition (EMT) gene expression. Related to Figure 2. Supplementary Figure 3. GSK-J4 inhibits stem cell-like properties of osteosarcoma cells. Related to Figure 3. Supplementary Figure 4. GSK-J4 treatment results in stemness related gene inactivation. Related to Figure 4. Supplementary Figure 5. LIF activates NOTCH1 signaling pathway. Related to Figure 5. Supplementary Figure 6. Crenigacestat suppresses NOTCH1 signaling pathway genes. Related to Figure 6. Supplementary Table 1. Primers used in this study</p>