Figure S4 from The FACT inhibitor CBL0137 Synergizes with Cisplatin in Small-Cell Lung Cancer by Increasing <i>NOTCH1</i> Expression and Targeting Tumor-Initiating Cells

Abstract

&lt;p&gt;Supplementary Fig S4. FACT is involved in the expression of regulatory stem cell transcription factors in TICs. A and B, CD44high cells derived from H446 and CD133high cells derived from H526 were treated with 500 nM (H446) or 1µM (H526) CBL0137 for 24 h. The mRNA levels of SOX2 were analyzed by qPCR (A), and SOX2 protein levels were determined by Western analysis (B).&lt;/p&gt;