Figure S6 from RAC1b Overexpression Confers Resistance to Chemotherapy Treatment in Colorectal Cancer

Abstract

<p>Figure S6. (A) Five different colorectal cancer cells showing the sensitivity for GYS32661, KRAS and BRAF mutation and Rac1b expression. (B) HCT116-EV and HCT116-Rac1b cells stably expressing the NFκÎ' reporter was treated with different dose of GYS32661. The cells were lysed in reporter lysis buffer and NFκB reporter activity was measured. The results, presented as the NF-kB-mediated luciferase activity normalized to the protein concentration are the means {plus minus} SEM from three independent experiments. (C) Mice body weight following treatment with GYS32661.</p>