Filarial huge splenomegaly dramatically regressed by anti-filarial medication: A rare clinical scenario

Extra-lymphatic manifestation of filariasis, especially as acute renal failure, is uncommon and may be clinically unsuspected. We document the case of a 60 year old elderly male who presented with bilateral pedal oedema, fatigue and abdominal distension. Investigations revealed severe anaemia, splenomegaly and acute renal failure. Bone marrow aspiration was performed to evaluate the clinical suspicion of malignancy. Out of eight smears examined, microfilaria ( Brugia malayi) were identified in two. This presentation was devoid of peripheral eosinophilia. The patient was commenced on a regimen of diethylcarbamazine, on which he made a good recovery. The incidence of extra-lymphatic filariasis is largely unknown and sparsely reported. Such a presentation should be kept in mind by both clinicians and pathologists as it is potentially treatable.

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“…Basu et al. 10 described a similar case as ours having splenomegaly, but with prior evidence of parasitic infestation.…”

Section: Discussionsupporting

confidence: 65%

Filariasis presenting with bicytopenia, progressive splenomegaly and acute renal failure: An unusual case report

2021

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“…A retrospective analysis of the records of our outpatient clinics and infectious disease consultations from 2017 revealed 20 patients of proven filariasis. Five patients showed atypical presentations, with the findings of one among them (massive splenomegaly with bone marrow aspirate showing microfilariae) having been already published (4).…”

Section: Discussionmentioning

confidence: 99%

Atypical cases of filariasis from a non-endemic area

Kodan

Gupta

Baidya

et al. 2018

DD&T

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Filariasis can present in many different ways and pose significant dilemma to the clinician. We report four atypical cases of filariasis which presented as abdominal mass, cervical lymph node enlargement, fever in pregnancy and nosocomial febrile illness respectively. All the four cases were treated successfully with oral antifilarial agents. It is essential to be aware of such atypical presentations of filariasis so that prompt therapy can be initiated.

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Unexpected Discoveries: Eosinophilia Unmasked by Splenic Microfilariasis in a Young Woman

Kazi,

Shinde,

Rumani

et al. 2024

Tjh

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Filarial huge splenomegaly dramatically regressed by anti-filarial medication: A rare clinical scenario

Cited by 3 publications

References 7 publications

Filariasis presenting with bicytopenia, progressive splenomegaly and acute renal failure: An unusual case report

Filariasis presenting with bicytopenia, progressive splenomegaly and acute renal failure: An unusual case report

Atypical cases of filariasis from a non-endemic area

Unexpected Discoveries: Eosinophilia Unmasked by Splenic Microfilariasis in a Young Woman

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