We report a diode-pumped continuous-wave tri-wavelength Nd:LuVO 4 laser operating at 916, 1086, and 1089 nm. A theoretical analysis has been introduced to determine the threshold conditions for simultaneous tri-wavelength laser operation. Using a T-shaped cavity, we realized efficient tri-wavelength operation at 4 F 3/2 → 4 I 9/2 and 4 F 3/2 → 4 I 11/2 transitions for Nd:LuVO 4 crystal, simultaneously. The maximum output power was 2.8 W, which included 916, 1086, and 1089 nm, and the optical conversion efficiency was 15.1%. To our knowledge, this is the first work that realizes simultaneous tri-wavelength Nd:LuVO 4 laser operation.