Fingernail psoriasis reconsidered: A case-control study

Velden, Haike M.J. van der; Klaassen, Karlijn M.G.; Kerkhof, P.C.M. van de; Pasch, Marcel C.

doi:10.1016/j.jaad.2013.02.009

Cited by 63 publications

(80 citation statements)

References 33 publications

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“…Further descriptive demographic patient characteristics are summarized in table 1 and have been extensively analysed in a previous article by van der Velden et al [3]. …”

Section: Resultsmentioning

confidence: 99%

“…Patients who were unable to fill in the questionnaire because of illiteracy or mental impairment or who had suffered a recent serious life event that could affect their present experienced QoL were also excluded. We have previously studied the clinical features of fingernail psoriasis in the above-mentioned patient group [3]. …”

Section: Methodsmentioning

confidence: 99%

“…The prevalence of nail disease among psoriasis patients varies between 10 and 81%, and the reported lifetime incidence in psoriatic patients is 80-90% [1]. The characteristics of nail psoriasis are pitting, onycholysis, splinter haemorrhages, subungual hyperkeratosis, red spots in the lunula, oil drop discoloration, leukonychia and nail plate crumbling, which can be divided into nail matrix and nail bed symptoms [2,3]. Psoriatic nail lesions rarely appear as the only clinical manifestation of psoriasis, as psoriasis limited to the nails occurs in only 1-18% of patients with psoriasis [2,4,5].…”

Section: Introductionmentioning

confidence: 99%

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The Impact of Fingernail Psoriasis on Patients' Health-Related and Disease-Specific Quality of Life

et al. 2014

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Background: The impact of various dermatological conditions on quality of life (QoL) has been extensively studied, however the impact of nail psoriasis on QoL is an underexplored area. Objective: To investigate the impact of fingernail psoriasis on patients' QoL. Methods: A cross-sectional observational study using validated questionnaires concerning QoL (SF-36, modified onychomycosis questionnaire) was performed in 49 patients with fingernail psoriasis. Results: The mean SF-36 scores for fingernail psoriasis patients were comparable to the mean scores of the Dutch reference population. However, mean scores on the modified onychomycosis QoL questionnaire for all domains were reduced. Localisation, gender and duration of nail psoriasis influenced the impact of nail psoriasis on patients' QoL. Conclusion: Fingernail psoriasis can interfere with patients' social, mental and physical well-being. Assessing patients' QoL in daily practice offers the opportunity of a patient-centred approach to treatment.

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“…Further descriptive demographic patient characteristics are summarized in table 1 and have been extensively analysed in a previous article by van der Velden et al [3]. …”

Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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The Impact of Fingernail Psoriasis on Patients' Health-Related and Disease-Specific Quality of Life

et al. 2014

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“…6,7 Therefore, it is important for clinicians to be able to diagnose nail psoriasis clinically, through observation for classic nail matrix and nail bed manifestations. Nail matrix manifestations include pitting, leukonychia, red spots in the lunula, and nail plate crumbling.…”

Section: Patient Education Suggestions For Nail Psoriasismentioning

confidence: 99%

“…At any given time, between 50-66% of psoriasis patients have nail manifestations, with a lifetime prevalence of 80-90%. 6,7 Isolated nail psoriasis is present in 5-10% of patients. 8,9 Though the degree of nail involvement and types of nail changes present varies among patients, in many cases, nail psoriasis can cause disability by compromising the normal structure and function of the nail.…”

mentioning

confidence: 99%

Clinical Manifestations and Management Considerations of Psoriasis Affecting The Nail Unit

Desai¹,

Rosso²,

Lebwohl³

2019

J of Skin

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Psoriasis is a chronic, inflammatory disease with a diverse array of clinical manifestations involving the skin, joints, and nails. Of these, nail psoriasis is a frequently overlooked, yet important complication of psoriasis which can cause significant physical and psychological distress to a patient. Psoriasis affecting the nail unit can pose both diagnostic and therapeutic challenges to physicians due to its clinical heterogeneity, the multitude of available treatment options, and the general lack of high-quality research on the subject. In order to aid the practicing clinician in appropriate diagnosis and treatment of nail psoriasis, this review provides an overview of the epidemiological, clinical, and pathophysiologic features of the disease, while also attempting to develop a rationale for effective medical management of the condition.

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