Aiming at the problem of network delay when the network control system transmits data, this paper adopts a new type of fuzzy control method of Smith predictor to compensate for the delay. In actual application scenarios, it is difficult to accurately match the Smith prediction model with the actual model. At the same time, the quantization factor and scale factor in the fuzzy PID controller are too dependent on experience, which makes the system’s adaptability to actual working conditions very poor. In this paper, genetic algorithm is used to optimizes fuzzy PID. According to the simulation results, when the Smith predictive model does not match the actual model, the steady-state performance and dynamic performance of the system under the fuzzy PID control optimized by the genetic algorithm are improved.