First isolation of Mycobacterium canariasense from municipal water supplies in Tenerife, Canary Islands, Spain

Lecuona, Marı́a; Abreu, Rossana; Rodríguez-Álvarez, Cristobalina; Castro, Beatriz; Campos, Sílvia B.; Hernández-Porto, Miriam; Mendoza, Pablo; Arias, Á.

doi:10.1016/j.ijheh.2015.08.005

Cited by 8 publications

(3 citation statements)

References 37 publications

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“…To our knowledge, our case is the first one describing infective endocarditis caused by M. canariasense with life-threatening complications because of systemic embolization and valvular destruction requiring surgical valve replacement. It is likely that water used to dissolve the recreational drugs was contaminated with this pathogen and was the source of infection in our patient because M canariasense has been reported in water ( Azadi et al, 2014, Lecouna et al, 2016. Therefore, it is important to consider this organism in susceptible populations because the choice of antimicrobial, duration of therapy, and prognosis differ significantly compared with other infective etiologies manifesting similarly.…”

Section: Discussionmentioning

confidence: 94%

First case report of Mycobacterium canariasense native mitral valve endocarditis

Hassan

Owaisi

et al. 2022

International Journal of Infectious Diseases

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Section: Discussionmentioning

confidence: 94%

First case report of Mycobacterium canariasense native mitral valve endocarditis

Hassan

Owaisi

et al. 2022

International Journal of Infectious Diseases

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“…Because NTM are commonly found in water, especially in drinking-water distribution systems (24,(47)(48)(49)(50)(51)(52)(53) and tap water (54,55), municipal water supplies may be viewed as a potential source of infection. Colorado represents a unique geographic and hydrologic system where, to a large extent, we can separate the potential effect of source water from that of municipal water by using watersheds as a unit of exposure.…”

Section: Watershed Effectmentioning

confidence: 99%

A Geospatial Epidemiologic Analysis of Nontuberculous Mycobacterial Infection: An Ecological Study in Colorado

et al. 2017

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Rationale: Nontuberculous mycobacteria (NTM) are ubiquitous environmental microorganisms. Infection is thought to result primarily from exposure to soil and/or water sources. NTM disease prevalence varies greatly by geographic region, but the geospatial factors influencing this variation remain unclear.Objectives: To identify sociodemographic and environmental ecological risk factors associated with NTM infection and disease in Colorado. Methods:We conducted an ecological study, combining data from patients with a diagnosis of NTM disease from National Jewish Health's electronic medical record database and ZIP code-level sociodemographic and environmental exposure data obtained from the U.S. Geological Survey, the U.S. Department of Agriculture, and the U.S. Census Bureau. We used spatial scan methods to identify high-risk clusters of NTM disease in Colorado. Ecological risk factors for disease were assessed using Bayesian generalized linear models assuming Poisson-distributed discrete responses (case counts by ZIP code) with the log link function.Results: We identified two statistically significant high-risk clusters of disease. The primary cluster included ZIP codes in urban regions of Denver and Aurora, as well as regions south of Denver, on the east side of the Continental Divide. The secondary cluster was located on the west side of the Continental Divide in rural and mountainous regions. After adjustment for sociodemographic, drive time, and soil variables, we identified three watershed areas with relative risks of 12.2, 4.6, and 4.2 for slowly growing NTM infections compared with the mean disease risk for all watersheds in Colorado. This study population carries with it inherent limitations that may introduce bias. The lack of complete capture of NTM cases in Colorado may be related to factors such as disease severity, education and income levels, and insurance status.Conclusions: Our findings provide evidence that water derived from particular watersheds may be an important source of NTM exposure in Colorado. The watershed with the greatest risk of NTM disease contains the Dillon Reservoir. This reservoir is also the main water supply for major cities located in the two watersheds with the second and third highest disease risk in the state, suggesting an important possible source of infection.

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“…NTMs are usually ubiquitous in the environment and are opportunistic pathogens that can cause a wide range of infections, among which lung infections are the most common (70-80%). Unlike MTB, NTM can survive in municipal water supplies with poor nutrition, where they are able to form bio lms and are resistant to chlorinated disinfectants [1,2] . A series of nosocomial outbreak or pseudo-outbreaks studies have revealed that the presence of these NTMs in hospital water supply network served as main source, and contaminated medical equipment or solution caused healthcare-associated infections [3][4][5] .…”

Section: Introductionmentioning

confidence: 99%

A nosocomial outbreak of Mycobacterium Abscessus infection in a private hospital of Shanghai, China, 2021

Liu,

Jiang,

Shi

et al. 2023

Preprint

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Background: Mycobacterium abscessus is a rapid-growing mycobacterium, and it is often present in the water supply of hospital. Here we describe an outbreak of M. Abscessus infection in a private hospital in Shanghai, the epidemiological investigation and control measures were also conducted. Methods: From September 27th to October 1st, 2021, four consecutive AFB-positive patients from same ward in a private hospital who were first suspected of MTB infection were reported to Putuo district Center for Disease Control. Bronchial lavage fluids were sampled from all inpatients for both Mycobacterium culture and metagenome sequencing analysis (mNGS). Epidemiological investigation and environmental examination were conducted during this outbreak. Findings: Three of the four index patients had positive culture result for M. abscessus, while mNGS showed positive sequencing results in all 4 patients. However, 32 environmental samples from different sources were negative for M. abscessus. A series of infection control measures were strictly performed, and no further cases were reported in one year follow up. Conclusions: This nosocomial outbreak was caused by M. abscessus but the accurate source remains uncertain. The unique pathogen was captured by mNGS, and this sequencing technique can play an important role in identifying nosocomial outbreak.

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First isolation of Mycobacterium canariasense from municipal water supplies in Tenerife, Canary Islands, Spain

Cited by 8 publications

References 37 publications

First case report of Mycobacterium canariasense native mitral valve endocarditis

First case report of Mycobacterium canariasense native mitral valve endocarditis

A Geospatial Epidemiologic Analysis of Nontuberculous Mycobacterial Infection: An Ecological Study in Colorado

A nosocomial outbreak of Mycobacterium Abscessus infection in a private hospital of Shanghai, China, 2021

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