“…The patients were in very good health before transplantation. Immunosuppressive treatment included basiliximab in induction and triple drug therapy based on tacrolimus, mycophenolate mofetil, and prednisone at doses presented earlier [10].…”
“…The patients were in very good health before transplantation. Immunosuppressive treatment included basiliximab in induction and triple drug therapy based on tacrolimus, mycophenolate mofetil, and prednisone at doses presented earlier [10].…”
“…In addition, functional outcomes were overall poorer than those reported by other centers around the world. [37][38][39][40] The results of bilateral above the elbow transplants were reported in 2012, after 19 and 30 months of follow-up. 41 Both patients were able to flex the elbow with 160-and 180-degree range of motion in the fingers of the grafted limb, and DASH scores improved.…”
Section: Overview Of Hand Transplant and Outcomesmentioning
“…[1][2][3][4][5][6] However, the risks of rejection and side effects in the course of clinical treatment were not eliminated. As a result, numerous MPA modifications together with their biological evaluations were reported.…”
The total synthesis of mycophenolic acid (MPA), a potent immunosuppressant, was modified. The obtained mycophenolic acid was suitable for further preparation of new prospective immunosuppressants with improved therapeutic properties.
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