Five Year Incidence of Visual Field Loss in Adult Chinese. The Beijing Eye Study.

Abstract

PurposeTo describe the cumulative 5 year incidence of visual field loss in adult Chinese in Greater Beijing.MethodsThe Beijing Eye Study 2006 included 3251 subjects (mean age 60.4±10.1 years) who had participated in the Beijing Eye Study 2001 and returned for re-examination. All participants underwent a comprehensive eye examination, including visual field test by frequency doubling threshold perimetry. An abnormal visual field was defined as reduced sensitivity in at least one test location. Incident visual field loss was defined as a change in visual field from normal at baseline to abnormal at follow-up.ResultsAn incident visual field loss was detected in 273 eyes (4.3±0.5%) /235 subjects (7.3±0.5%). It was significantly associated with higher age (P = 0.001), higher intraocular pressure (P<0.001), and higher fasting blood glucose concentration (P = 0.019). Considering only eyes (n = 140) with a detected cause for visual field loss, the most frequent causes were cataract (68 (48.6%) eyes) followed by glaucoma (23 (16.4%) eyes), diabetic retinopathy (13 (9.3%) eyes), age-related macular degeneration (10 (7.1%) eyes), and myopic degenerative retinopathy (9 (6.4%) eyes). For 133 (48.7%) eyes with a visual field loss, the cause for the VFL remained unclear.ConclusionsThe 5-year incidence of visual field loss was 4.3±0.5% per eye or 7.3±0.5% per subject. It increased significantly with age, intraocular pressure, and fasting blood glucose level. Major causes for the incidence of visual field loss were cataract, glaucoma and diabetic retinopathy.

The Montrachet Study: study design, methodology and analysis of visual acuity and refractive errors in an elderly population

“…An abnormal frequency doubling perimetry was defined as at least one location of reduced sensitivity of any level (Wang et al. ).…”

10-Year Incidence and Associations of Pterygium in Adult Chinese: The Beijing Eye Study

“…The details of participants and nonparticipants at baseline and the 5-year follow-up examination as well as the examinations performed have been described elsewhere. 15,16 All study participants underwent an interview by trained health staff with standardized questions on their family status, level of education, income, quality of life, psychic depression, physical activity, known major systemic diseases such as arterial hypertension and diabetes mellitus, and intake of systemic medication. Fasting blood samples were taken for measurement of blood lipids, glucose, and glycosylated hemoglobin HbA1c.…”

MiR-542-5p regulates the progression of diabetic retinopathy by targeting CARM1

“…DR mainly causes vision loss and blindness in adults worldwide (Chong et al, 2017;Klein, 2007;Cheung et al, 2010). The incidence of DR has been increasing annually worldwide (Wang et al, 2012;Klein et al, 2017). Laser photocoagulation treatment shows no significant improvement in visual acuity in the long term (Liu et al, 2019).…”