“…23,[342][343][344][346][347][348]350 Therapy can be repeated with ease, risk of complications is minimal, and early to midterm results in case series are equivalent to or better than those reported after conventional perforating vein interruptions. [356][357][358] The risks of open procedures, which specifically include infection, difficulty in healing of incisions required for treatment, increased local trauma, and need for general anesthesia, set open operations apart from these less invasive percutaneous methods.…”