Fixed low-dose perindopril 2 mg/indapamide 0.625 mg combination in very elderly hypertensives

Forette, B.

doi:10.1038/sj.jhh.1000779

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Calcium Antagonists1

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Cited by 6 publications

(1 citation statement)

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“…Peripheral edema also may be confused with HF. 581 Verapamil, which may be useful for LV diastolic dysfunction, may increase constipation. 582 Verapamil and diltiazem [585][586][587][588] progression of diabetic renal disease, 589 and progression of hypertensive nephrosclerosis.…”

Section: Calcium Antagonistsmentioning

confidence: 99%

ACCF/AHA 2011 Expert Consensus Document on Hypertension in the Elderly

Aronow

Fleg

Pepine

et al. 2011

Journal of the American Society of Hypertension

122

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Section: Calcium Antagonistsmentioning

confidence: 99%

ACCF/AHA 2011 Expert Consensus Document on Hypertension in the Elderly

Aronow

Fleg

Pepine

et al. 2011

Journal of the American Society of Hypertension

122

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A systematic review and meta-analysis of the efficacy and safety of a fixed, low-dose perindopril-indapamide combination as first-line treatment of hypertension

Kang

et al. 2004

Clinical Therapeutics

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Efficacy of very low dose perindopril 2 mg/indapamide 0.625 mg combination on left ventricular hypertrophy in hypertensive patients: the P.I.C.X.E.L. study rationale and design

et al. 2002

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The PICXEL study is designed to evaluate the effects of long-term administration of very low-dose combination perindopril 2 mg/indapamide 0.625 mg (Per/Ind) vs enalapril in reducing left ventricular hypertrophy (LVH) in hypertensive patients. This multicentre, controlled, randomised, double-blind, parallel group study is carriedout to assess the variation of left ventricular mass index (LVMI) after treatment, using a centralised control of Mmode echocardiography determinations, and a dedicated software for semi-automatic measurement. Following a 4-week placebo run-in period, hypertensive outpatients aged у18 years, with LVH (LVMI Ͼ120 and 100 g/m 2 for men and women, respectively), are randomised to receive once daily, over 52 weeks, either Per/Ind or enalapril. According to blood pressure levels, the dose may be adjusted. In addition to clinical examinations, ECG, blood pressure, heart rate and laboratory assessments echocardiographic determinations are performed for selection, at baseline, after 24 weeks and

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Fixed low-dose perindopril 2 mg/indapamide 0.625 mg combination in very elderly hypertensives

Cited by 6 publications

References 6 publications

ACCF/AHA 2011 Expert Consensus Document on Hypertension in the Elderly

ACCF/AHA 2011 Expert Consensus Document on Hypertension in the Elderly

A systematic review and meta-analysis of the efficacy and safety of a fixed, low-dose perindopril-indapamide combination as first-line treatment of hypertension

Efficacy of very low dose perindopril 2 mg/indapamide 0.625 mg combination on left ventricular hypertrophy in hypertensive patients: the P.I.C.X.E.L. study rationale and design

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