FLASHlight MRI in real time—a step towards Star Trek medicine

Michaelis, Thomas; Voit, Dirk; Kollmeier, Jost M.; Kalentev, Oleksandr; Zalk, Maaike van; Frahm, Jens

doi:10.21037/qims-22-648

Cited by 1 publication

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References 20 publications

(25 reference statements)

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“…New real-time MRI technologies [ 136 ] suggest that breathing also plays an important role in the correct estimation of lumbar and intracranial pressure. Additionally, the novel mapping [ 137 , 138 ] and FLASHlight [ 139 ] methods may also provide new approaches for non-invasive ICP measurements.…”

Section: Approaches Of Non-invasive Measurementsmentioning

confidence: 99%

Non-Invasive Intracranial Pressure Monitoring

Müller

Henkes

Gounis³

et al. 2023

JCM

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(1) Background: Intracranial pressure (ICP) monitoring plays a key role in the treatment of patients in intensive care units, as well as during long-term surgeries and interventions. The gold standard is invasive measurement and monitoring via ventricular drainage or a parenchymal probe. In recent decades, numerous methods for non-invasive measurement have been evaluated but none have become established in routine clinical practice. The aim of this study was to reflect on the current state of research and shed light on relevant techniques for future clinical application. (2) Methods: We performed a PubMed search for “non-invasive AND ICP AND (measurement OR monitoring)” and identified 306 results. On the basis of these search results, we conducted an in-depth source analysis to identify additional methods. Studies were analyzed for design, patient type (e.g., infants, adults, and shunt patients), statistical evaluation (correlation, accuracy, and reliability), number of included measurements, and statistical assessment of accuracy and reliability. (3) Results: MRI-ICP and two-depth Doppler showed the most potential (and were the most complex methods). Tympanic membrane temperature, diffuse correlation spectroscopy, natural resonance frequency, and retinal vein approaches were also promising. (4) Conclusions: To date, no convincing evidence supports the use of a particular method for non-invasive intracranial pressure measurement. However, many new approaches are under development.

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