Flavone C- and/or O-glycosides from corn silk

Ali, Z; Sarfare, S; Walker, LA; Khan, IA

doi:10.1055/s-0035-1545215

Cited by 1 publication

(1 citation statement)

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“…To our pleasure, these C-glycosyl flavones F I G U R E 3 The schematic diagram for fragmentation pathway of luteolin and luteolin act out multiple similar pharmacological activities like anti-diabetic, anti-inflammatory, anti-hepatotoxic, anti-oxidative, anti-allergic, etc. [13,[28][29][30]. Among various activities, anti-diabetic and anti-inflammatory play a bright-eyed role in pharmacological research ( Figure 4B).…”

Section: Characterization Of Chemical Constituents From Corn Silkmentioning

confidence: 99%

Rapid discovery and global characterization of multiple components in corn silk using a multivariate data processing approach based on UHPLC coupled with electrospray ionization/quadrupole time‐of‐flight mass spectrometry

Liu

Fan

et al. 2018

J of Separation Science

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Corn silk is an important traditional Chinese medicine which has been widely used as diuretic, antilithiasic, uricosuric, antiseptic, etc. for thousands of years. However, it is a pity that the chemical ingredients in corn silk, especially the constituents absorbed into blood, are unclear up to now. The aim of our study was to investigate the multiple components of corn silk in vitro and in vivo. In this present study, a sensitive and rapid method using ultra high performance liquid chromatography coupled with electrospray ionization/quadrupole time-of-flight tandem mass spectrometry and a multivariate data processing approach was established to detect the constituents of corn silk in vitro and in vivo. Consequently, total 41 ingredients in vitro and 19 of them absorbed into blood including luteolin, various C-glycosyl flavones, jasmonic acid, abscisic acid, gibberellin A, etc. were tentatively characterized in sequence. Furthermore, of particular importance, a kind of stable compound named C-glycosyl flavones is a great discovery in vivo, which can point the further pharmacological study target in future. In a word, this is the first serum pharmacochemistry study of corn silk, which played a critical role in exploring the pharmacological and effective data for further research.

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Section: Characterization Of Chemical Constituents From Corn Silkmentioning

confidence: 99%