Flavonoids as Nutraceuticals: A Review

Tapas, A. R.; Sakarkar, D. M.; Kakde, RB

doi:10.4314/tjpr.v7i3.14693

Cited by 674 publications

(431 citation statements)

References 54 publications

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“…Although flavonoids are biologically versatile compounds well known for their positive impact on human health (antidiabetic, anti-inflammatory, hepatoprotective and cardioprotective properties (Champ 2002; Tapas et al 2008), studies on mushrooms are scanty (Barros et al 2008; Gursoy et al 2009). Flavonoids significantly decreased in cooked A. hygrometricus ( p < 0.05) (Figure 2(c)), however, its content was substantially lower than uncooked and cooked T. umkowaan (Karun et al 2016b).…”

Section: Resultsmentioning

confidence: 99%

Bioactive potential of the wild mushroom Astraeus hygrometricus in South-west India

et al. 2016

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The wild mushroom Astraeus hygrometricus is a traditional delicacy during the monsoon season in South-western India. Bioactive principles and antioxidant potential of uncooked and pressure-cooked tender mushroom have been evaluated. Seven bioactive principles of mushroom (tannins, flavonoids, vitamin C, phytic acid, lycopene, β-carotene and trypsin inhibition) were significantly higher, while total phenolics content was significantly lower in uncooked than in cooked samples. Mushroom was devoid of L-DOPA, whereas only uncooked samples showed haemagglutinin activity against A+ blood group. The principal component analysis of uncooked mushroom showed only two bioactive principles clustered with two antioxidant properties, while in cooked mushroom five bioactive principles clustered with three antioxidant properties depicting the nutraceutical potential of cooked mushroom. Future studies should focus on appropriate thermal treatment, which retain maximum bioactive and antioxidant potential to combat health- and lifestyle-related ailments. The A. hygrometricus is ectomycorrhizal, conservation of its host tree species is utmost importance in improvement and expansion of its yield to sustain food security and economic gains of local tribals.

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Section: Resultsmentioning

confidence: 99%

Bioactive potential of the wild mushroom Astraeus hygrometricus in South-west India

et al. 2016

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“…Flavonoids and tannins have been reported to inhibit prostaglandin synthesis (Alcaraz & Ferrandiz, 1987). It is ubiquitously known that flavonoids have a great potential as anti-inflammatory agents (Tapas et al, 2008;Tuñón et al, 2009;Serafini et al, 2010). Therefore, we postulated that flavonoids in the extract may correlate appropriately for the present activities.…”

Section: Chan Pit Foong and Roslida Abdul Hamidmentioning

confidence: 99%

Evaluation of anti-inflammatory activities of ethanolic extract of Annona muricata leaves

Foong

Hamid

2012

Rev. bras. farmacogn.

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Traditionally, the leaves of Annona muricata L., Annonaceae, are used to treat headaches, fever, toothache, cough and asthma. The decoction of the leaves has parasiticide, antirheumatic and antineuralgic effects when used internally, while the cooked leaves, applied topically, fight rheumatism and abscesses. The aim of this study was to investigate acute and chronic anti-inflammatory potential of an ethanolic leaf extract of A. muricata (AML) in animal models. The ethanolic extract of A. muricata leaf extract was prepared and administered orally to experimental animals used. The anti-inflammatory activity was determined by xylene-induced ear edema in mice and Complete Freund's adjuvant (CFA)-induced arthritis in rats. The results demonstrated that AML is effective for both acute and chronic inflammation. It also significantly attenuated both TNF-α and IL-1β levels in CFAinduced arthritis model. Thus, these results have suggested that AML possesses both anti-inflammatory and anti-arthritic activities. The findings also suggest that AML presents notable anti-arthritic activity that may be mediated by suppressing proinflammatory cytokines.

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“…Flavonoids are also polyphenolic compounds and have been reported to have multiple biological activities which include antimicrobial, cytotoxicity, anti-inflammatory, anti-tumor, anti-allergy, vascular-and oestrogenic activities. Flavonoids' most important bioactivity is that they are powerful antioxidants thus allowing them to scavenge free radicals and protect the body from reactive oxygen species [47,48].…”

Section: Minimum Inhibitory Concentration (Microdilution Method)mentioning

confidence: 99%

Phytochemical Screening, GCxGC TOF-MS Analysis and Antibacterial Properties of Crude Rhoicissus Ttomentosa Rhizome Extract

2016

International Conference on Advances in Science, Engineering, Technology and Natural Resources (ICASETNR-16) Nov. 24-25, 2016 P

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Abstract-Rhoicissus tomentosa is a plant used in South Africantraditional medicine to treat ailments mainly related to fertility and reproduction. Phytochemical screening was carried out and the antimicrobial activity of the rhizomes of R. tomentosa was investigated for the first time to ascertain their possible pharmaceutical potential. The results showed that the rhizomes of the plant contain alkaloids, flavonoids, saponins, steroids, reducing sugars and tannins. GCxGC-TOF-MS analysis of the extracts displayed the presence of over 100 known bioactive compounds, many reported here and detected in Rhoicissus tomentosa for the first time. Methanol: chloroform (50/50, v/v) and ethyl acetate (100%) extracts of the rhizomes were tested against 14 bacterial strains using the disc diffusion and microdilution assay methods. Bacteria most susceptible to rhizome extracts were Staphylococcus aureus (0.063 mg/mL) and Bacillus subtilis (0.125 mg/mL). The results obtained show that the rhizomes of R. tomentosa have antimicrobial activity against a number of pathogenic microorganisms.

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Flavonoids as Nutraceuticals: A Review

Abstract: Abstract

Cited by 674 publications

References 54 publications

Bioactive potential of the wild mushroom Astraeus hygrometricus in South-west India

Bioactive potential of the wild mushroom Astraeus hygrometricus in South-west India

Evaluation of anti-inflammatory activities of ethanolic extract of Annona muricata leaves

Phytochemical Screening, GCxGC TOF-MS Analysis and Antibacterial Properties of Crude Rhoicissus Ttomentosa Rhizome Extract

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