Flavonoids from the Leaf Resin of Snakeweed, Gutierrezia sarothrae

Hradetzky, Dagmar; Wollenweber, Eckhard; Roitman, James N.

doi:10.1515/znc-1987-1-212

Cited by 8 publications

(4 citation statements)

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“…Exudate flavonoids have been reported from G. sarothrae (Pursh) Britt. (Hradetzky et al, 1987); in the same paper, the occurrence of flavonoid aglycones in extracts of G. grandis and of G. microcephala is commented. Similar substitution trends have been observed in all species studied so far, as is also evident from results on G. wrightii (Fang et al, 1986).…”

Section: Flavonoid Aglycones Of Astereae Speciesmentioning

confidence: 95%

Chemodiversity of Exudate Flavonoids in Seven Tribes of Cichorioideae and Asteroideae (Asteraceae)

Valant–Vetschera

Wollenweber

2007

Zeitschrift Für Naturforschung C

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Members of several genera of Asteraceae, belonging to the tribes Mutisieae, Cardueae, Lactuceae (all subfamily Cichorioideae), and of Astereae, Senecioneae, Helenieae and Heliantheae (all subfamily Asteroideae) have been analyzed for chemodiversity of their exudate flavonoid profiles. The majority of structures found were flavones and flavonols, sometimes with 6-and/or 8-substitution, and with a varying degree of oxidation and methylation. Flavanones were observed in exudates of some genera, and, in some cases, also flavonol-and flavone glycosides were detected. This was mostly the case when exudates were poor both in yield and chemical complexity. Structurally diverse profiles are found particularly within Astereae and Heliantheae. The tribes in the subfamily Cichorioideae exhibited less complex flavonoid profiles. Current results are compared to literature data, and botanical information is included on the studied taxa.

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Section: Flavonoid Aglycones Of Astereae Speciesmentioning

confidence: 95%

Chemodiversity of Exudate Flavonoids in Seven Tribes of Cichorioideae and Asteroideae (Asteraceae)

Valant–Vetschera

Wollenweber

2007

Zeitschrift Für Naturforschung C

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“…Natural Product Communications Vol. 11 (6) 2016 721 (28.6 mg). Fractions F3-3 (IC 50 around 2.5 µg/mL) and F3-4 (IC 50 between 2.5~5 µg/mL) were combined and further separated by HPLC on a semipreparative C 18 column (Phenomenex Luna column, 5 µm, 250 x 10 mm) eluted with a solvent gradient from CH 3 CN:H 2 O, 50:50 to 60:40 from 0 to 10 min, to 100:0 from 10 to 30 min, ending with 100% CH 3 CN from 30 to 40 min at a flow rate of 2.5 mL/min.…”

Section: Gutierrezia Diterpenesmentioning

confidence: 99%

“…The plant has been used externally to treat bee stings, snake bites, flesh wounds [3], and rheumatism [4]. Previous studies have indicated that the plant contains monoterpenes [5], volatile components such as cryptone and β -eudesmol [2], flavonoids [6], and labdane derivatives [7a,7b]. An antitumor proteinaceous substance has also been reported from the plant [8].…”

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New Antiplasmodial Diterpenes from Gutierrezia Sarothrae

Dalal

Goetz

et al. 2016

Natural Product Communications

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Bioassay guided fractionation of the MeOH extract of the plant Gutierrezia sarothrae (Asteraceae) using an assay for antiplasmodial activity against the drug-resistant Dd2 strain of Plasmodium falciparum led to the isolation of the two new diterpenes 3α-angeloyloxy-15-hydroxylabda-7,13-dien-16,15-olid-18-oic acid (1) and 3α-angeloyloxy-15-methoxylabda-7,13-dien-16,15-olid-18-oic acid (2). The structures of 1 and 2 were elucidated by interpretation of 1D and 2D NMR spectroscopic data, mass spectrometry, and comparison with the data of related compounds reported in the literature. Compound 1 exhibited moderate antiplasmodial activity with an IC50 values of 10.4 ± 4.3 µM.

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“…There have been previous investigations of the essential oil composition of G. sarothrae from New Mexico and from Utah, USA [35][36][37]. Diterpenoids, including polyalthic acid, daniellic acid, nivenolide, and gutierrezial [31][32][33], and flavonoids, including apigenin, luteolin, calycopterin, jaceidin, sudachitin, and sarothrin [34], have been isolated and characterized from G. sarothrae extracts. The plant is an invasive weed and there have been several reports on the toxic effects of livestock grazing on G. sarothrae, causing abortions [30].…”

Section: Introductionmentioning

confidence: 99%

The Essential Oil Compositions of Ambrosia acanthicarpa Hook., Artemisia ludoviciana Nutt., and Gutierrezia sarothrae (Pursh) Britton & Rusby (Asteraceae) from the Owyhee Mountains of Idaho

Swor,

Poudel,

Satyal

et al. 2024

Molecules

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As part of our interest in the volatile phytoconstituents of aromatic plants of the Great Basin, we have obtained essential oils of Ambrosia acanthicarpa (three samples), Artemisia ludoviciana (12 samples), and Gutierrezia sarothrae (six samples) from the Owyhee Mountains of southwestern Idaho. Gas chromatographic analyses (GC-MS, GC-FID, and chiral GC-MS) were carried out on each essential oil sample. The essential oils of A. acanthicarpa were dominated by monoterpene hydrocarbons, including α-pinene (36.7–45.1%), myrcene (21.6–25.5%), and β-phellandrene (4.9–7.0%). Monoterpene hydrocarbons also dominated the essential oils of G. sarothrae, with β-pinene (0.5–18.4%), α-phellandrene (2.2–11.8%), limonene (1.4–25.4%), and (Z)-β-ocimene (18.8–39.4%) as major components. The essential oils of A. ludoviciana showed wide variation in composition, but the relatively abundant compounds were camphor (0.1–61.9%, average 14.1%), 1,8-cineole (0.1–50.8%, average 11.1%), (E)-nerolidol (0.0–41.0%, average 6.8%), and artemisia ketone (0.0–46.1%, average 5.1%). This is the first report on the essential oil composition of A. acanthicarpa and the first report on the enantiomeric distribution in an Ambrosia species. The essential oil compositions of A. ludoviciana and G. sarothrae showed wide variation in composition in this study and compared with previous studies, likely due to subspecies variation.

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Flavonoids from the Leaf Resin of Snakeweed, Gutierrezia sarothrae

Cited by 8 publications

References 0 publications

Chemodiversity of Exudate Flavonoids in Seven Tribes of Cichorioideae and Asteroideae (Asteraceae)

Chemodiversity of Exudate Flavonoids in Seven Tribes of Cichorioideae and Asteroideae (Asteraceae)

New Antiplasmodial Diterpenes from Gutierrezia Sarothrae

The Essential Oil Compositions of Ambrosia acanthicarpa Hook., Artemisia ludoviciana Nutt., and Gutierrezia sarothrae (Pursh) Britton & Rusby (Asteraceae) from the Owyhee Mountains of Idaho

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