2008
DOI: 10.1016/j.phytochem.2008.05.003
|View full text |Cite
|
Sign up to set email alerts
|

Flavonols and an oxychromonol from Piliostigma reticulatum

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1
1

Citation Types

2
25
0
1

Year Published

2010
2010
2020
2020

Publication Types

Select...
6
2

Relationship

0
8

Authors

Journals

citations
Cited by 36 publications
(28 citation statements)
references
References 24 publications
2
25
0
1
Order By: Relevance
“…The characteristically chelated 5-OH group was observed at δ 12.92 while that of 4'-OH was observed δ 10.90. By careful comparison of the 13 C NMR data of 4 with existing literature (Roitman and James, 1985;Breitmeier and Voelter, 1990;Babajide et al, 2008), the 4'-substituent was assigned to a hydroxyl hydroxyl group while that at the 3' position was assigned as a methoxyl group. Corroboration of this deduction was evident from chemical shifts of the substituted carbons, viz., C-3' at δ 147.2 and C-4' at 148.5.…”
Section: Discussion and Resultsmentioning
confidence: 87%
See 2 more Smart Citations
“…The characteristically chelated 5-OH group was observed at δ 12.92 while that of 4'-OH was observed δ 10.90. By careful comparison of the 13 C NMR data of 4 with existing literature (Roitman and James, 1985;Breitmeier and Voelter, 1990;Babajide et al, 2008), the 4'-substituent was assigned to a hydroxyl hydroxyl group while that at the 3' position was assigned as a methoxyl group. Corroboration of this deduction was evident from chemical shifts of the substituted carbons, viz., C-3' at δ 147.2 and C-4' at 148.5.…”
Section: Discussion and Resultsmentioning
confidence: 87%
“…The brine shrimp lethality biossay was carried out as previously described ( Babajide et al, 2008( Babajide et al, , 2010 where about 2 g of the Brine shrimp eggs (Artemia salina Leach) were hatched in 2 L of sea water using a large plastic case as an artificially partitioned dam. The number of dead nauplii were counted and recorded (lethality data) after 24 h. The numbers of dead nauplii were used for calculating the LC 50 at 95% confidence limit by the Finney Probit analysis program.…”
Section: Brine Shrimp Lethality Biossaymentioning
confidence: 99%
See 1 more Smart Citation
“…In addition, piliostigmin, a 2-phenoxychromone, quercetin, quercitrin, 6-C-methylquercetin 3-methyl ether, 6-C-methylquercetin 3,7,3'-trimethyl ether, 6,8-di-C-methylkaempferol 3-methyl ether and 6,8-di-C-methylkaempferol 3,7-dimethyl ether were isolated from the leaves of P. thonningii (Ibewuike et al, 1996). Similar C-methylated flavonols and the oxychromonol isolated from Piliostigma reticulatum showed antimicrobial activity and toxicity in brine shrimp lethality assay (Babajide et al, 2008). Flavonol glycosides afzelin, quercitrin and myricitrin isolated from another plant, e.g.…”
Section: Resultsmentioning
confidence: 91%
“…To the best of our knowledge, the antidiarrhoeal properties of the stem bark of this plant have not been investigated. However, chemical compounds isolated from P. reticulatum, such as flavonols (6-C-methylquercetin-3-methyl ether-5; 6,8-di-Cmethylkaempferol-3-methyl ether-6 and 6-C-methylquercetin-3,3',7-trimethyl ether-7) and oxychromonol (6-C-methyl-2-p-hydroxyphenyloxychromonol, or piliostigmol), have been shown to exhibit antimicrobial activities against bacteria (Escherichia coli and Bacillus subtilis) and fungi (Aspergillus niger and Candida albicans) that cause infectious diarrhoeas (Babajide et al, 2008). Furthermore, antidiarrhoeal activity of the roots of P. reticulatum has been reported by Salawu et al (2007).…”
Section: Introductionmentioning
confidence: 99%