2023
DOI: 10.1101/2023.10.17.562819
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FLI1 localization to the chlamydial inclusion involves multiple mechanisms

Natalie A. Sturd,
Macy G. Wood,
Legacy Durham
et al.

Abstract: Following entry into a host cell, the obligate intracellular pathogen, Chlamydia trachomatis, establishes an intracellular niche within a membrane derived vacuole called the chlamydial inclusion. The resulting inclusion membrane is modified by the pathogen and is a hybrid host-chlamydial structure. From within this intracellular niche, C. trachomatis must orchestrate numerous host-pathogen interactions to surreptitiously acquire nutrients from its host and to limit detection by the host innate immune system. C… Show more

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