Flow-facilitated ring opening metathesis polymerization (ROMP) and post-polymerization modification reactions

Abstract

Continuous flow facilitates ROMP reactions to prepare homopolymers and block copolymers and allows for in-line post-polymerization click modifications.

Enabling technologies in polymer synthesis: accessing a new design space for advanced polymer materials

“…28 Literature for the similarly named ring opening metathesis polymerisation (ROMP) is much more sparse and recent; only a single paper showing the polymerisation of norbornene derivatives. 73 Finally, anionic polymerisation has also been demonstrated, from work in the 1960s 52 to use of more modern continuous reactors. [74][75][76] Tubular and microfluidic reactors comprised of transparent material also present a particular opportunity for light-induced polymerisations since they allow for much more thorough irradiation of the reaction mixture due to reduced path lengths relative to batch reactors.…”

“…28 Literature for the similarly named ring opening metathesis polymerisation (ROMP) is much more sparse and recent; only a single paper showing the polymerisation of norbornene derivatives. 73 Finally, anionic polymerisation has also been demonstrated, from work in the 1960s 52 to use of more modern continuous reactors. 74–76…”

A Transient Initiator for Polypeptoids Postpolymerization α‐Functionalization via Activation of a Thioester Group

“…[ 104 ] Postpolymerization modification (PPM) can help to overcome limitations that occur during polymerization and introduce responsive, structural, and functional properties into polymers, which are otherwise incompatible with the polymerization process. [ 36,105–108 ] PPM can offer several advantages. On one hand, a variety of different functionalities can be introduced into the side chain or termini of a polymer.…”

A transient initiator for polypeptoids post-polymerization α-functionalization via activation of thioester group

“…Later, Johann and co-workers introduced the aminofunctional trans-cyclooctenes (TCO) and 6-methyl-tetrazine (mTz) as initiators to obtain functional polypeptoids and performed their post-polymerization modification [104]. Postpolymerization modification (PPM) can help to overcome limitations that occur during polymerization and introduce responsive, structural and functional properties into polymers, which are otherwise incompatible with the polymerization process [36,[105][106][107][108]. PPM can offer several advantages.…”