Fluid dynamics and intraocular pressure using venturi phacoemulsification machine in dogs ex vivo

Kang, Seonmi; Park, Sangwan; Noh, Hyunwoo; Seo, Kangmoon

doi:10.1111/vop.12231

Cited by 6 publications

(10 citation statements)

References 16 publications

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“…A previous human study suggested that a reduction in the incisional outflow induced by vitreous plugging of the CCI might increase the static pressures after a PLCR . The IOP fluctuation during phacoemulsification was reported to be determined by the balance between the influx affected by the irrigating fluid and the efflux affected by the aspirating fluid and the leakage through the CCI . Therefore, in addition, the vitreous plugging of the phaco needle or IA tip might act as a flow restrictor, thereby decreasing the efflux of the aspirating fluid and lens materials and hence increasing the IOP during the surgery.…”

Section: Discussionmentioning

confidence: 99%

“…Phacoemulsification was subdivided into two stages: the sculpt‐segment removal (SS) stage, which involved the use of a phacoemulsification handpiece with a 19 G, straight 30° needle (Storz® DP8130, Bausch and Lomb, Rochester, NY, USA), and a soft silicone sleeve, and the irrigation/aspiration (IA) stage, which involved an IA handpiece with a 20 G, 0.3‐mm aspiration port tip (Storz® DP9745, Bausch and Lomb), and a soft silicone sleeve. On the basis of our previous studies, the BHs/vacuum pressures were set at 60 cm/100 mmHg, respectively, as a low fluidic setting for three eyes and at 90 cm/170 mmHg, respectively, as a high fluidic setting for the other three eyes during the SS stage. The IA stage was performed with BHs/vacuum pressures of 60 cm/450 mmHg and 90 cm/450 mmHg for the low and high fluidic settings, respectively.…”

Section: Methodsmentioning

confidence: 99%

“…Real‐time IOP measurements during phacoemulsification has been performed in several human and canine studies . Indeed, it was demonstrated that directly measuring IOP is equivalent to the theoretical pressure and hence it was possible to objectively evaluate the effect of the IOP on the eye during surgery in these studies.…”

Section: Introductionmentioning

confidence: 99%

“…Indeed, it was demonstrated that directly measuring IOP is equivalent to the theoretical pressure and hence it was possible to objectively evaluate the effect of the IOP on the eye during surgery in these studies. It was also found that the IOP fluctuated during phacoemulsification, while the fluidic parameters influenced the range of the IOP fluctuations …”

Section: Introductionmentioning

confidence: 99%

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Influence of an intentionally induced posterior lens capsule rupture on the real‐time intraocular pressure during phacoemulsification in canine ex vivo eyes

Kang

Park

et al. 2017

Veterinary Ophthalmology

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Objective To evaluate the changes in the intraocular pressure (IOP) following an intentionally induced posterior lens capsule rupture (PLCR) during phacoemulsification in enucleated canine eyes. Furthermore, to compare the IOPs between different stages of phacoemulsification for two different bottle heights (BH). Procedures Coaxial phacoemulsification was performed using a venturi-based machine at a 60 or 90 cm BH. A pressure transducer, inserted into the anterior chamber through the peripheral cornea, monitored real-time IOP. For one half of the lens, the sculpt-segment removal (SS) was followed by irrigation/aspiration (IA). The PLCR was intentionally created, and the SS and IA were repeated on the residual lens fragments. Results For the 60 cm BH, the mean IOP following the PLCR was significantly higher than before the PLCR during SS (28.30 AE 12.56 and 38.71 AE 9.43 mmHg before and after PLCR, respectively) and IA (42.76 AE 12.46 and 47.88 AE 7.10 mmHg before and after PLCR, respectively) stages (P < 0.001). For the 90 cm BH, the mean IOP following the PLCR was also significantly higher than before the PLCR during SS (33.39 AE 11.09 and 58.17 AE 6.89 mmHg before and after PLCR, respectively) and IA (62.39 AE 12.46 and 72.04 AE 8.59 mmHg before and after PLCR, respectively) stages (P < 0.001).Conclusions The occurrence of a PLCR led to an increase in IOP during both the SS and IA stages. The elevated IOP after the PLCR might be one of the most important factors for ocular tissue damage, as it reduces ocular perfusion. Additionally, the BH should be reduced following PLCR to prevent complications stemming from the raised IOP.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Influence of an intentionally induced posterior lens capsule rupture on the real‐time intraocular pressure during phacoemulsification in canine ex vivo eyes

Kang

Park

et al. 2017

Veterinary Ophthalmology

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“…Ex vivo models have been used to study a variety of different ocular diseases in different species . One important benefit of an ex vivo model is that it allows for a more adequate representation of in vivo conditions.…”

Section: Introductionmentioning

confidence: 99%

Development of a novel ex vivo equine corneal model

Marlo

Giuliano

Sharma

et al. 2016

Veterinary Ophthalmology

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Objective To develop an ex vivo equine corneal organ culture model. Specifically, to assess the equine cornea's extracellular matrix and cellularity after 7 days using two different culture techniques: either (a) immersion system or (b) air/liquid interface system, to determine the best ex vivo equine corneal model. Methods Fourteen healthy equine corneas with 2 mm of perilimbal sclera were freshly harvested from 7 horses undergoing humane euthanasia. One corneal-scleral ring (CSR) from each horse was randomly placed in the (a) immersion condition organ culture system (IC), with the contralateral SCR being placed in the (b) air/liquid interface organ culture system (ALC) for 7 days. All corneas were evaluated using serial daily gross photography, histology, qPCR and TUNEL assay. Results CSRs placed in the IC (a) had complete loss of corneal transparency on gross photography by 7 days, showed a significant level of corneal stromal disorganization, significantly increased αSMA levels on qPCR, and apoptosis on TUNEL assay compared to controls. The ALC (b), had weak stromal disorganization on histopathologic examination and was not significantly different from normal equine corneal controls on all other evaluated parameters. Conclusions The air-liquid interface organ culture system maintains the equine cornea's extracellular matrix and preserves corneal transparency, while the immersion condition results in near complete degradation of normal equine corneal architecture after 7 days in culture. The air-liquid organ culture is a viable option to maintain a healthy equine cornea in an ex-vivo setting for wound healing studies.

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Surgical Procedures of the Lens and Cataract

Gelatt

Gelatt²,

Plummer³

2022

Veterinary Ophthalmic Surgery

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Fluid dynamics and intraocular pressure using venturi phacoemulsification machine in dogs ex vivo

Abstract: BH during the I/A stage could be reduced to avoid unnecessary stress on the canine eye when using a venturi system. Although phacoemulsification with a 3.2-mm CCI could induce lower IOP, a 3.0-mm CCI might lessen the irrigation flow stress on the eye.

Cited by 6 publications

References 16 publications

Influence of an intentionally induced posterior lens capsule rupture on the real‐time intraocular pressure during phacoemulsification in canine ex vivo eyes

Influence of an intentionally induced posterior lens capsule rupture on the real‐time intraocular pressure during phacoemulsification in canine ex vivo eyes

Development of a novel ex vivo equine corneal model

Surgical Procedures of the Lens and Cataract

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