Background:The antibacterial effect and cariostatic properties of glass -ionomer cement are associated with the amount of fluoride released ,therefore the aim of the study was to evaluate fluoride release from three different glass ionomer cement (GIC)-based restorative materials .Materials and methods :a total of 42 samples of extracted caries free permanent molars were obtained as 14 samples in each group .group A(FujiIX:resin modified glass ionomer cement),group B (Voco:TGIC) and group C (Ketac Molar) each tooth was prepared for conventional class I cavity preparation , followed by application of the restorative material then kept in artificial saliva to be examined for fluoride release after 48hours,7,15,28 days using Orion fluoride electrode.Results: according to this study ,there is different in fluoride release between the study groups according to the time interval ,where group A showed the statistically significant value in relation to group B&C(P<0.005).Conclusions :this study showed that FujiIX was the material of the highest fluoride release value.KEY WORD : fluoride release, glass ionomer cement, fujiix, vovo, ketac molar .