“…Our goal is to address the limitations of NORF in terms of solubility, hydration stability, and diffusion permeability through crystal engineering. Numerous reports are available on NORF solid forms such as cocrystals, − salts, − polymorphs, − hydrates, − and eutectics to improve its physicochemical properties. NORF forms metal complexes with Cu, Tb, Ni, Ti, Cr, Mn, Fe, Ba, V, Zn, Cd, Mg, Ag, W, Co, Pd, and Bi. − NORF cocrystals have been reported with isonicotinamide and salt-cocrystals with saccharin, terephthalic acid, and hexadienoic acid.…”