Flurbiprofen does not change the bispectral index and 95% spectral edge frequency during total intravenous anaesthesia with propofol and fentanyl

Sevoflurane requirement during elective ankle day surgery: the effects of etirocoxib premedication, a prospective randomised study

“…We provided induction and analgesics in as standardised doses as possible, however titrating sevoflurane to maintain the EEG derived depth of anaesthesia monitoring in a rather narrow pre-defined range during surgery. A study design quit different from that of Hirota et al, where a dose of NSAIDs was added to a steady-state intra-venous anaesthesia without and surgical stimulation [ 18 ]. In disagreement with their hypothesis they could see no change in BIS from the addition of a conventional non-selective NSAID.…”