Foam Sclerotherapy: Techniques and Uses

Bunke, Nisha; Brown, Katherine Kay; Bergan, John J.

doi:10.1177/1531003509345286

Cited by 13 publications

(8 citation statements)

References 6 publications

(7 reference statements)

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“…Foam sclerotherapy is a variation of the method. With foam, air bubbles displace blood, allowing the agent to have more direct contact with the lesion's endothelium and exerting a greater effect than liquid alone (which is diluted in blood) . Subsequently, a lesser amount of active drug is necessary to treat the lesion successfully.…”

Section: Discussionsupporting

confidence: 90%

Prospective randomized trial of sclerotherapy vs standard treatment for epistaxis due to hereditary hemorrhagic telangiectasia

Boyer

Fernandes

et al. 2015

Int Forum Allergy Rhinol

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Background Our previous studies have demonstrated the tolerability and low side-effect profile of office-based sclerotherapy with sodium tetradecyl sulfate (STS) for treating recurrent epistaxis due to hereditary hemorrhagic telangiectasia (HHT). The objective of this study was to use a prospective randomized trial to determine the effectiveness of sclerotherapy with STS vs standard treatment. Methods This prospective randomized trial (conducted from November 1, 2011, through January 31, 2014) involved 17 patients with recurrent epistaxis due to HHT. We defined standard treatment as continuation of any treatment that the patient had previously undergone, such as moisturization, packing, and cautery. We used a crossover design, so study participants were randomized to either sclerotherapy or standard treatment during the first time period, and then to the other during the second period. The primary outcome measure was frequency and severity of epistaxis, as measured by the epistaxis severity score (ESS). The ESS is a 10-point scale, with higher scores corresponding to more bleeding. Results After controlling for treatment order, bleeding was substantially better controlled after sclerotherapy; the ESS after sclerotherapy was nearly one point lower than after standard treatment (−0.95, 1-sided p = 0.027). Treatment order, baseline ESS, the number of lesions, moisturization practices, and a history of previous blood transfusions did not significantly affect the results. Conclusion This trial demonstrated that sclerotherapy with STS (vs standard treatment) significantly reduced epistaxis due to HHT.

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Section: Discussionsupporting

confidence: 90%

Prospective randomized trial of sclerotherapy vs standard treatment for epistaxis due to hereditary hemorrhagic telangiectasia

Boyer

Fernandes

et al. 2015

Int Forum Allergy Rhinol

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show abstract

“…Foam sclerotherapy is a popular variation of the method. The advantage is air bubbles allow the agent to have a more direct contact with the lesion's endothelium, giving a greater effect than liquid alone, which is diluted in blood 55. Subsequently, a lesser amount of active drug is necessary to treat the lesion successfully.…”

Section: Discussionmentioning

confidence: 99%

Office‐based sclerotherapy for recurrent epistaxis due to hereditary hemorrhagic telangiectasia: a pilot study

Boyer

Fernandes

Durán

et al. 2011

Int Forum Allergy Rhinol

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“…Importantly, FS seems to be especially useful in the patients who have difficulty tolerating multilayer compression bandaging or in patients who are not suitable for elevation leg therapy. 3,16,17 There is also the consideration that many patients with VLU may not be candidates for surgery on account of age and comorbidities or they do not agree to be operated on, even if no medical contraindications for such treatments exist. By comparison, most of these patients ideally qualify for FS of incompetent superficial and perforating veins.…”

Section: The Use Of Foam Sclerotherapy In Patients With Leg Ulcersmentioning

confidence: 99%

Principles and Technique of Foam Sclerotherapy and Its Specific Use in the Treatment of Venous Leg Ulcers

Simka¹

2011

The International Journal of Lower Extremity Wounds

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Invention of foam sclerotherapy has significantly changed the current phlebological practice. Compared with liquid sclerosants, obliterating foam is more efficient, especially for the closure of larger veins. This review discusses clinical aspects of foam sclerotherapy with a focus on its use for the treatment of venous leg ulceration, including the rationale for its use in the treatment of these chronic wounds, physicochemical mechanisms responsible for stability and disintegration of sclerosant foam, pathomechanism of neurologic adverse events seen after foam sclerotherapy, and techniques that can increase efficacy of this procedure and lower frequency of adverse events.

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Foam Sclerotherapy: Techniques and Uses

Cited by 13 publications

References 6 publications

Prospective randomized trial of sclerotherapy vs standard treatment for epistaxis due to hereditary hemorrhagic telangiectasia

Prospective randomized trial of sclerotherapy vs standard treatment for epistaxis due to hereditary hemorrhagic telangiectasia

Office‐based sclerotherapy for recurrent epistaxis due to hereditary hemorrhagic telangiectasia: a pilot study

Principles and Technique of Foam Sclerotherapy and Its Specific Use in the Treatment of Venous Leg Ulcers

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