Focus issue on diagnostic work-up and prognostic assessment in cardiac disease

Focus issue on cardiomyopathies

“…Diagnosis of cardiac sarcoidosis can be difficult given the patchy myocardial infiltration, but can be aided by the use of advanced cardiac imaging such as cardiac magnetic resonance (CMR) [2]. CMR is recommended and frequently used for the diagnosis and prognostication of patients with suspected cardiac sarcoidosis.…”

“…Three main types of amyloidosis associated with cardiac involvement are acknowledged: light chain (AL), familial or senile (ATTR) and secondary amyloidosis (AA). The diagnosis is suggested in the presence of cardiac or extracardiac red flags and/or in specific clinical situations and confirmed by the use of bone scintigraphy coupled to assessment for monoclonal proteins [2,6]. Debonnaire et al reported the trends in diagnosis, referral routes, clinical presentation, early onset diagnostic red flags and outcome in 139 de novo cardiac amyloidosis subjects recruited over a 8-year period in a tertiary referral hospital [7].…”