Focused Update of 2016 Korean Society of Heart Failure Guidelines for the Management of Chronic Heart Failure

Kim, Kyungjin; Cho, Hyun‐Jai; Kim, Min-Seok; Kang, Jeehoon; Kim, Kyung‐Hee; Kim, Darea; Seo, Suk Min; Yang, Jeong Hoon; Cha, Myung‐Jin; Choi, Jong Il; Choi, Dong‐Ju

doi:10.36628/ijhf.2019.0002

Cited by 46 publications

(32 citation statements)

References 70 publications

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“…MetS is more common in men than women until 50 years of age, while this sex difference is attenuated during aging [ 11 ]. Given the increased burden of metabolic components during the transition period between 50 and 60 years of age, it is important to understand the impact of dysmetabolic changes on cardiac remodeling, which characterizes the early stage of overt heart failure [ 7 , 13 ].…”

Section: Introductionmentioning

confidence: 99%

Longitudinal Change in Myocardial Function and Clinical Parameters in Middle-Aged Subjects: A 3-Year Follow-up Study

et al. 2021

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Background: Metabolic syndrome (MetS) is closely associated with the aging process. However, changes in metabolic conditions and cardiac function that occur in middle aged population remain unclear. We evaluated longitudinal changes in metabolic parameters and cardiac function during a 3-year period in subjects with suspected MetS. Methods: We studied 191 participants with suspected MetS at baseline and after 3 years. Anthropometric parameters, including waist circumference (WC), and metabolic parameters, including fasting blood glucose and lipid profile were measured. Conventional echocardiography with two-dimensional speckle tracking was performed. Results: Mean age was 56.2±4.4 years, and there were 97 women (50.8%). Men had increased WC and triglycerides (TG) (WC 91.2±6.8 cm vs. 84.0±8.0 cm, P<0.001; TG 184.4±116.3 mg/dL vs. 128.2±53.6 mg/dL, P<0.001), and reduced global longitudinal strain (GLS) (-15.4%±2.1% vs. -17.1%±2.0%, P<0.001) compared to women. After 3.4 years, values of WC and TG did not change in men but increased in women (all P<0.05). The absolute value of left ventricular (LV) GLS did not change in men but was reduced in women (P=0.011). Change in TG was independently associated with worsening of LV GLS only in women (standardized β, -0.309; 95% confidence interval, -0.130 to -0.009; P=0.025). Conclusion:In middle aged population, a vulnerable period for metabolic disturbance, cardiac remodeling tended to progress, which was prominent in women. Progression of adiposity and dyslipidemia after menopause may accelerate subclinical cardiac remodeling in middle-aged women. Lifestyle modification and medical interventions may help prevent further cardiac dysfunction in these subjects.

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Section: Introductionmentioning

confidence: 99%

Longitudinal Change in Myocardial Function and Clinical Parameters in Middle-Aged Subjects: A 3-Year Follow-up Study

et al. 2021

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“…3A ) [ 65 ]. In the KorAHF registry, 59.1%, 15.8%, and 25.1% had HFrEF, HFmrEF, and HFpEF, respectively [ 66 ]. Among patients with diabetes 64%, 14.4%, and 21.6% had HFrEF, HFmrEF, and HFpEF, respectively.…”

Section: Diagnosis Of Heart Failurementioning

confidence: 99%

Epidemiology, Pathophysiology, Diagnosis and Treatment of Heart Failure in Diabetes

Park

2021

Diabetes Metab J

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The cardiovascular disease continuum begins with risk factors such as diabetes mellitus (DM), progresses to vasculopathy and myocardial dysfunction, and finally ends with cardiovascular death. Diabetes is associated with a 2- to 4-fold increased risk for heart failure (HF). Moreover, HF patients with DM have a worse prognosis than those without DM. Diabetes can cause myocardial ischemia via micro- and macrovasculopathy and can directly exert deleterious effects on the myocardium. Hyperglycemia, hyperinsulinemia, and insulin resistance can cause alterations in vascular homeostasis. Then, reduced nitric oxide and increased reactive oxygen species levels favor inflammation leading to atherothrombotic progression and myocardial dysfunction. The classification, diagnosis, and treatment of HF for a patient with and without DM remain the same. Until now, drugs targeting neurohumoral and metabolic pathways improved mortality and morbidity in HF with reduced ejection fraction (HFrEF). Therefore, all HFrEF patients should receive guideline-directed medical therapy. By contrast, drugs modulating neurohumoral activity did not improve survival in HF with preserved ejection fraction (HFpEF) patients. Trials investigating whether sodium-glucose cotransporter-2 inhibitors are effective in HFpEF are on-going. This review will summarize the epidemiology, pathophysiology, and treatment of HF in diabetes.

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“…1) During the outbreak of COVID-19, a balanced strategy to ensure the safety of HT recipient and medical staff is crucial in the consideration of each individual circumstance (Figure 4). [1][2][3][4][5] https://e-kcj.org https://doi.org/10.4070/kcj.2020.0177…”

Section: Conflict Of Interestmentioning

confidence: 99%

Successful Heart Transplantation to a Fulminant Myocarditis Patient during COVID-19 Outbreak – Lessons Learned

et al. 2020

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A 42-year-old female without previous medical history visited for febrile sensation, myalgia, and shortness of breath for two days. Her entrance to the emergency room (ER) was delayed due to the triage process during the coronavirus disease 2019 (COVID-19) outbreak. Mild cardiomegaly with left atrial enlargement on chest X-ray and ST-elevation on electrocardiography were noted (Figure 1). Sudden cardiac arrest developed at ER and immediate extracorporeal membrane oxygenation was applied. No coronary obstruction was present. The test for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) was negative and the repeated tests consistently showed negative results. On postadmission day 5, there was only p wave without corresponding ventricular conduction on electrocardiography (Figure 2) which was correlated with echocardiographic finding (Supplementary Video 1). We put the patient for heart transplantation (HT) waitlist due to the aggravating course of fulminant myocarditis. Three days later, a 27-year-old male donor was matched with negative crossmatch result. The donor test of SARS-CoV-2 revealed negative. The hospital organ procurement organization in other region hesitated to allow the

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Focused Update of 2016 Korean Society of Heart Failure Guidelines for the Management of Chronic Heart Failure

Cited by 46 publications

References 70 publications

Longitudinal Change in Myocardial Function and Clinical Parameters in Middle-Aged Subjects: A 3-Year Follow-up Study

Longitudinal Change in Myocardial Function and Clinical Parameters in Middle-Aged Subjects: A 3-Year Follow-up Study

Epidemiology, Pathophysiology, Diagnosis and Treatment of Heart Failure in Diabetes

Successful Heart Transplantation to a Fulminant Myocarditis Patient during COVID-19 Outbreak – Lessons Learned

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