Folic Acid Ionic-Liquids-Based Separation: Extraction and Modelling

Blaga, Alexandra Cristina; Drăgoi, Elena Niculina; Tucaliuc, Alexandra; Kloetzer, Lenuţa; Caşcaval, Dan

doi:10.3390/molecules28083339

Cited by 8 publications

(4 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The reproductive period is between the ages of 15-49. Many young girls become pregnant before they have reached the height and body mass typical for the age of a young woman, and pregnancy during puberty is a relatively common phenomenon [32][33][34][35]. A deficiency in folic acid at the time of conception is strongly linked to the risk of congenital defects of the brain and spine.…”

Section: Discussionmentioning

confidence: 99%

Analysis of vitamin intake among pupils aged 7–18 living in rural areas of the Podbeskidzie region

Waksmańska¹,

Bobiński²,

Ilczak³

2023

Med Og Nauk Zdr.

View full text Add to dashboard Cite

Introduction and Objective.Research into the dietary habits of specific groups of children and adolescents is important from the public health perspective due to the possibilities for modifying any existing irregularities. The aim of the study was to assess the intake levels of vitamins in the daily diets of children and adolescents living in rural areas. Materials and method. The research used a study questionnaire containing questions on food products consumed every day from all 12 food groups, including: sweetened drinks, snacks, ready meals, sweets and fast food, as well as purchases made in the school shop, vitamin supplements and minerals consumption and dietary habits. Weight and height of each student were measured, BMI value calculated. The study participants comprised 332 pupils aged 7-9 years, 376 aged 10-12, 333 aged 13-15, and 139 aged 16-18. Results. In the study group, insufficient body weight was noted in 4.5% of pupils, excessive weight in 11%, and obesity in 10%. In all the groups of pupils, irrespective of age, the average daily intake of water soluble vitamins (with the exception of folic acid) met the Recommended Dietary Allowance. The average daily intake of vitamin A for all pupils exceeded the RDA. In vitamin D, even the maximum daily intake across all age groups did not meet the AI. Conclusions. The amount of vitamins in the diet was not in line with recommendations on correct dietary habits and, as such, requires the implementation of educational activities on the correct composition of the diet, in particular the variety of foodstuffs consumed. The daily supply of vitamin D was insufficient, and therefore must be supplemented, in particular during the autumn and winter seasons.

show abstract

Section: Discussionmentioning

confidence: 99%

Analysis of vitamin intake among pupils aged 7–18 living in rural areas of the Podbeskidzie region

Waksmańska¹,

Bobiński²,

Ilczak³

2023

Med Og Nauk Zdr.

View full text Add to dashboard Cite

show abstract

“…The main factors investigated in the reactive extraction of muconic acid were pH, temperature, extractant concentration, and time [49][50][51][52]. It was demonstrated that the pH of the aqueous phase has a significant impact on carboxylic acid reactive extraction [15][16][17][18][19]. In reactive extraction, MA can interact with the extractant in one of two ways: (I) by hydrogen-bonding with the undissociated acid molecule, or (II) by the formation of ion pairs when MA is dissociated (pH > pKa), Figure 5.…”

Section: Reactive Extraction Influencing Factorsmentioning

confidence: 99%

“…The reactive extraction approach has recently drawn more attention as a viable and efficient way to remove carboxylic acids from the fermentation broth and is frequently carried out utilizing a combination of extractants and solvents [13][14][15][16][17][18][19]. The classic systems, which include amines or organophosphorus extractants dissolved in organic solvents, have been improved in a substantial number of research articles over the past few decades in terms of sustainability and efficiency [20][21][22][23][24][25][26].…”

Section: Introductionmentioning

confidence: 99%

Recent Advances in Muconic Acid Extraction Process

Blaga,

Gal,

Tucaliuc

2023

Applied Sciences

Self Cite

View full text Add to dashboard Cite

Due to its potential use in the production of new functional resins, bio-plastics, food additives, agrochemicals, and pharmaceuticals, muconic acid (MA), a high value-added bio-product with reactive dicarboxylic groups and conjugated double bonds, has attracted growing interest. Adipic acid, terephthalic acid, and trimellitic acid are examples of bulk compounds that can be produced using MA that are of high commercial importance. The development of biotechnological approaches for MA production has advanced greatly recently. The current analysis offers a thorough and organized summary of recent developments and difficulties in the extraction of MA. A variety of extractants are presented, along with any limitations and potential solutions. Finally, the possibilities for this field in light of its state, difficulties, and tendencies are explored.

show abstract

“…Furthermore, NTDs, which include defects of the spine (spina bifida), brain (anencephaly), as well as encephalocele, are congenital malformations conditions during the structural growth of the neural tube of newborn babies. FA use before and during the first weeks of pregnancy has been shown to reduce the risk of NTDs [7,8,9].…”

Section: Introduction 1folatementioning

confidence: 99%

A Review of Microfiltration Membrane in Separating Folic Acid from Fermented Dark Green Leafy Vegetables (DGLVs), Legumes, Beans, and Cereal for Nutraceutical Application

Susilowati,

Melanie

et al. 2023

ijmst

View full text Add to dashboard Cite

DGLVs (spinach, broccoli), legumes (soybean, mung bean, kidney bean), and cereal (corn) are well recognized for human health benefits due to the presence of natural folate (vitamin B9) with essential micronutrients. Folate is among the most unstable vitamins for the normal functions of the human body. The recent development of membrane-based methods for the separation of folic acid (FA) is reviewed from the selected literature and covers the result of significant research that has been performed in the last five years on the use of the microfiltration (MF) method. This is coupled with the fermentation process to support and achieve separation or recovery of FA from their selected plant-based food source. The nixtamalization, fermentation, separation, and purification of DGLVs, legumes, and beans, as well as corn, were conducted using the MF (pore size 0.15 µm) membrane separation method. The results showed that the MF membrane was able to separate FA components in permeate from fermented spinach and broccoli, soybean, mung bean, kidney bean, and corn, namely 7.14 and 3.79, 197.00, 325.37 and 242.93, and 121.10 µg/mL, respectively. Meanwhile, FA content in retentate from fermented spinach and broccoli, soybean, mung bean, kidney bean, and corn was 58.90 and 28.10, 362.07, 254.07 and 506.07, and 212.84 µg/mL, respectively. The applications of membrane techniques were used as an alternative to some unit operations in the solving of separation issues as well as the development of selected new fermented plant-based food sources. The contemporary pressure-driven membranes, such as MF, and the main applications were related to pre-treatment, selected fermented plant-based food sources, and alternative technology for extending the shelf life of natural folate. The utilization of MF membranes in the nutraceutical field holds significant promise, particularly in the creation of value-added products from minor compounds.

show abstract

Folic Acid Ionic-Liquids-Based Separation: Extraction and Modelling

Cited by 8 publications

References 43 publications

Analysis of vitamin intake among pupils aged 7–18 living in rural areas of the Podbeskidzie region

Analysis of vitamin intake among pupils aged 7–18 living in rural areas of the Podbeskidzie region

Recent Advances in Muconic Acid Extraction Process

A Review of Microfiltration Membrane in Separating Folic Acid from Fermented Dark Green Leafy Vegetables (DGLVs), Legumes, Beans, and Cereal for Nutraceutical Application

Contact Info

Product

Resources

About