Follicular occlusion triad associated with reticulate pigmentary disorder: Is there a genetic linkage?

Gandhi, Vijay; Verma, Prashant; Yadav, Pravesh

doi:10.4103/0019-5154.114001

Cited by 5 publications

(6 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Over the past few years, several cases of some variants of FOT have been reported. [4,5] Gandhi et al presented a case of FOT associated with reticulate pigmentary disorder in 2013. [4] Coincidentally, the man in our case had a similar symptom of reticulate pigmentary disorder in his perineum and buttocks.…”

Section: Discussionmentioning

confidence: 99%

“…[4,5] Gandhi et al presented a case of FOT associated with reticulate pigmentary disorder in 2013. [4] Coincidentally, the man in our case had a similar symptom of reticulate pigmentary disorder in his perineum and buttocks. Meyers et al presented a rare case with an extensive cluster of exophytic nodules that developed on his chin, which was also a variant of FOT.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Scrotal elephantiasis associated with follicular occlusion triad

Liu

Liu²,

Xu³

et al. 2019

Medicine

View full text Add to dashboard Cite

Rationale: Follicular occlusion triad (FOT) is an autosomal recessive inherited disease and no more than 3 variants of the triad have been reported. We give a report in which scrotal elephantiasis is a variant of FOT and further perform a literature review. Patient concerns: A 41-year-old man came to us because of a large scrotal cyst and generalized skin lesions that had occurred over the past 10 years. The generalized skin lesions consisted of hidradenitis suppurativa on the perineum and back, acne conglobata in the armpit, and dissecting cellulitis of the scalp. He took antibiotics for a long time but achieved poor effect. Furthermore, he told his father and elder brother also manifested such skin lesions. Diagnoses: Magnetic resonance showed a mass in the left scrotum with clear boundaries. A routine blood test showed a high leukocyte level of 12 × 10 9 /L and a hemoglobin content of 78 g/L. C-reactive-protein increased. Series of autoimmune antibody tests were negative. The postoperative pathologic findings showed that the mass was an epidermoid cyst, and hematoxylin and eosin staining showed hyperkeratosis of the skin as well as inflammatory and edematous changes. A diagnosis of a variant of FOT was made. Interventions: We removed skin abscesses and lesioned the inner part with hydrogen peroxide. Then we performed an excision of the scrotal lesion. Outcome: The patient recovered well and had no evidence of recurrence at a 16-month follow-up. Lessons: We reported a case in which scrotal elephantiasis was a variant of FOT and surgical intervention played an important role in secondary urologic diseases.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Scrotal elephantiasis associated with follicular occlusion triad

Liu

Liu²,

Xu³

et al. 2019

Medicine

View full text Add to dashboard Cite

show abstract

“…Hidradenitis suppurativa, associated with other manifestations of follicular occlusion is reported frequently in the past. Follicular occlusion tetrad is a condition that includes hidradenitis suppurativa, acne conglobata, dissecting cellulitis of the scalp and pilonidal sinus [3]. Women are more commonly affected than males.…”

Section: Discussionmentioning

confidence: 99%

A Case of Transverse Hand Deficiency with Acne Inversa and Facial Freckling: A New Association or Coincidence

2018

IJCED

View full text Add to dashboard Cite

show abstract

“…We found a total of 19 cases of complete forms of the FO triad and four cases of the tetrad, two complete and two lacking DCS . In addition, FO triad has been reported in association with the keratitis ichthyosis deafness (KID) syndrome .…”

Section: Follicular Occlusion Syndromementioning

confidence: 94%

“…Tetracycline‐type antibiotics were at least partially effective in sixcases and ampicillin in a single case . Isotretinoin was reported effective in one and local antiseptics in two cases . Pharmacotherapy combined with surgery has been suggested …”

Section: Follicular Occlusion Syndromementioning

confidence: 99%

Recognizing syndromic hidradenitis suppurativa: a review of the literature

Gasparic

Riis

Jemec

2017

Acad Dermatol Venereol

View full text Add to dashboard Cite

Hidradenitis suppurativa (HS) is an inflammatory skin disease causing painful inflammation and suppuration. It may occur in rare syndromes: follicular occlusion, Bazex-Dupré-Christol, Down's, KID, PAPASH, PASS, PASH, and SAPHO syndromes, as well as Dowling-Degos disease. An overview of syndromic HS may inform the search for aetiological factors in HS. PubMed, Ovid and Web of Science were systematically searched using '(hidradenitis OR acne invers*) AND (syndrome OR KID OR PASS OR PAPA OR PASH OR SAPHO OR bazex-dupre OR 'dowling degos' OR triad OR tetrad)' and Cochrane Library using 'hidradenitis OR acne invers*'. A total of 82 articles were included in the final review. We summarize 134 cases collected from the 82 included articles. The syndromes are discussed, focusing on etiopathogenesis, clinical presentation and treatment. This study is based on case reports; therefore, conclusions may be subject to the selection bias. These syndromes are rare; however, it is important to recognize them, as treating them may require a different approach. Three subtypes of syndromic hidradenitis are suggested: syndromes with known genetic abnormalities, syndromes characterized by follicular plugging or structural defects, and syndromes with possible autoinflammatory pathogenesis. There was no universally effective treatment for syndromic HS, and treatment was individualized.

show abstract

Follicular occlusion triad associated with reticulate pigmentary disorder: Is there a genetic linkage?

Cited by 5 publications

References 15 publications

Scrotal elephantiasis associated with follicular occlusion triad

Scrotal elephantiasis associated with follicular occlusion triad

A Case of Transverse Hand Deficiency with Acne Inversa and Facial Freckling: A New Association or Coincidence

Recognizing syndromic hidradenitis suppurativa: a review of the literature

Contact Info

Product

Resources

About