Forced expiratory volume in one second can predict SYNTAX score in patients with chronic obstructive pulmonary disease

Abstract

A b s t r a c t Background:The SYNTAX score is an angiographic score that predicts coronary artery disease (CAD) complexity. It has been shown to be useful for decision making about percutaneous coronary intervention or coronary artery bypass grafting among patients with CAD. Higher SYNTAX scores are indicative of more complex disease. Chronic obstructive pulmonary disease (COPD) is characterised by limitation of airflow. Measurement of forced expiratory volume in one second (FEV1) in spirometry is used for diagnosis and to determine the severity of the disease.Aim: To evaluate the relationship between FEV1 and SYNTAX score in patients with COPD.Methods: Seventy-eight patients with a previous diagnosis of COPD and 48 patients without COPD were enrolled. Spirometry and coronary angiography were performed in all patients. SYNTAX score was calculated and compared between the two groups. The correlation between FEV1 and SYNTAX score was analysed.Results: SYNTAX score was higher in patients with COPD than in patients without COPD (23.22 ± 12.10 vs. 17.92 ± 11.21, respectively; p = 0.013). Multivariate analysis demonstrated that COPD was independently predictive for intermediate and high SYNTAX score (odds ratio 4.833; 95% confidence interval 2.228-10.485; p < 0.001). Mean FEV1 (% predicted) was 64.7 ± 11.4 and negatively correlated with SYNTAX score in COPD group (r = -0.266 and p = 0.018). The receiver operating characteristic analysis yielded a cutoff value of 65.5 for the FEV1 to predict SYNTAX score ≥ 23, with sensitivity and specificity being 78.6% and 70%, respectively. Conclusions:COPD is a predictor of higher SYNTAX scores. FEV1 is associated with more severe and complex CAD.

Comparison of Syntax Score and Syntax Score Iı to Predict Peri-Procedural Myocardial İnjury during Percutaneous Coronary İntervention

“…Association between multiple vascular disease and COPD has been shown in studies [14,15]. In a study; have been shown that the patients with COPD who underwent PCI procedure had a higher incidence of myocardial injury [14].…”

Lower Urinary Tract Dysfunction in Multiple Sclerosis Patients

“…Patients with OABSS8 and above has 'overactive bladder' and 16 and above were considered as 'severe symptomatic patients' 15 . The severity of urinary tract symptoms, irritative and obstructive symptoms could be assessed individually by using IPSS 16 .…”

Early Invasive Versus Ischemia-Guided Strategy in Non-ST-Segment Elevation Acute Coronary Syndrome With Chronic Obstructive Pulmonary Disease: A National Inpatient Sample Analysis

“…Chronic obstructive pulmonary disease is a predictor of worse in-hospital survival in those presenting with ACS. 5 –8 The COPD cohorts were found to have more severe coronary artery disease on coronary angiography 9 –11 and lower utilization of β-blockers, statins, and coronary interventions. 6 –8 The guidelines for NSTE-ACS recommend early invasive strategy (EIS), invasive strategy, or ischemia-guided strategy (IGS) based on clinical presentation and high-risk comorbidities (ie, prior coronary artery bypass).…”