The issue of organizing the teaching of hygiene considering specialization of the medical university faculties is relevant in the context of digitalization. Proficiency in digital skill determines the modern professional physician’s competitiveness. The paper provides analysis of the use of digital technologies to study the relevant issues of hygiene. Educational process at the Department of General Hygiene of the Voronezh State Medical University is built on the principle of uniformity and consistency. Professional educational trajectory, including that on digital platforms, considers the teaching continuity, from fundamental theoretical subjects to clinical and specialized ones. Within the framework of educational process, issues of special hygiene, such as specifics of structure and use of medical institutions, features of professional activity of physicians of various specialties, are considered. Conventional methods to teach hygiene are supplemented with the differentially used innovative teaching techniques. The business game method is successfully used by the future clinicians to master the topic “Food Poisoning”. The method of creating educational videos for visual demonstration of laboratory work can be used in distant learning. The digital learning method demonstrates the possibility of using advanced digital devices and internet-based technologies in preventive medicine. It seems necessary to further improve the educational process at all the faculties as educational and professional standards, as well as the academic passport for Hygiene, are updated.