The article analyzes the genesis of the entrepreneurial university model and the experience of its Anglo-Saxon version transfer to the Russian institutional environment in 2010–2020: non-organic character of the entrepreneurial function in Russian universities, in the perception of both administrators and the bulk of the academics; closeness of some leading technical universities to external stakeholders (business angels and venturers) due to the secrecy of the research conducted; unwillingness and/or inability of the academics to invest own time and energy in the creation and conduct of business; failure of the administration to take into account the interests of teams of start-upers, which generates disbelief in the possibility of implementing a business project at the university; the focus of the university administration on supporting student entrepreneurship and underestimating or ignoring the need to create conditions for the development of entrepreneurial activity of academic staff. A new approach (“reassembly”) of a poorly working model based on a different understanding of the possibilities and actors of the “triple helix” is proposed, which may be more adequate under the current conditions.