Formulation and Evaluation of Polyherbal Anti-Acne Gel

Patil, Aboli; Patil, Aruna R; Patil, Aishwarya; Shid, Shubhangi; Dange, V.N.; Magduum, C.S.; Mohite, Shrinivas K.

doi:10.5958/2321-5844.2017.00007.3

Cited by 3 publications

(5 citation statements)

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“…Afterward, the combination above was added to the carbopol mixture and mixed well. Finally, with steady and continuous stirring, propylene glycol and triethanolamine were added to the dispersion in drops, and the pH was adjusted to 6.8-7.4 (neutralized) [ 17 , 39 ].…”

Section: Methodsmentioning

confidence: 99%

“…The above mixture was then added to the carbopol mixture and stirred well. Finally, propylene glycol and triethanolamine were added in drops to the dispersion with constant and continuous stirring, and also the pH was adjusted to 6.8-7.4 (neutralized) [ 17 ].…”

Section: Methodsmentioning

confidence: 99%

“…Official techniques were used to assess pH, colour, odour, consistency, texture, greasiness, homogeneity, grittiness, compatibility, drug content, viscosity, extrudability, and spreadability [ 17 , 40 – 43 ].…”

Section: Methodsmentioning

confidence: 99%

“…This study is aimed at formulating and evaluating the effectiveness of an active antiacne gel against P. aeruginosa and Staph. epidermidis with excellent synergistic effect against other microbial strains [17,[21][22][23][24][25][26].…”

Section: Introductionmentioning

confidence: 99%

“…Medicinal plants have the advantages of patient tolerance and wide acceptability [15]. For example, Azadirachta indica and Citrus aurantifolia have been folklorically used as antiacne agents [16][17][18]. Aloe vera, Allium cepa, and Eucalyptus globulus have antimicrobial, anti-inflammatory, and antioxidant activities that significantly treat skin infections.…”

Section: Introductionmentioning

confidence: 99%

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Formulation and Evaluation of Herbal‐Based Antiacne Gel Preparations

Ansong,

Asante,

Johnson

et al. 2023

BioMed Research International

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Acne vulgaris is an inflammatory skin condition that affects virtually everyone at some point. Papules, comedones, pustules, scarring, and nodules are standard features of the disease and can have a detrimental social and psychological impact on an individual. Although allopathic acne treatments are available, they have adverse side effects, are expensive, and are prone to cause antibiotic resistance. The present study is aimed at formulating and evaluating topical gels containing Aloe vera, Allium cepa, and Eucalyptus globulus extracts as potential antiacne drugs. Six formulations containing the herbal extracts were prepared using 1% Carbopol 940 as a gelling agent. The phytochemical composition of the plant extracts was determined. The extracts and gels’ minimum inhibitory concentration (MIC) was assessed using the microbroth dilution method. The physicochemical properties of the formulated gels, such as homogeneity, colour, texture, odour, grittiness, spreadability, extrudability, viscosity, pH, and drug content, were evaluated. All the plant extracts contained alkaloids, flavonoids, tannins, triterpenoids, and coumarins. The gel formulations showed varying activity against Staphylococcus epidermidis, Staphylococcus aureus, Escherichia coli, Candida albicans, and Pseudomonas aeruginosa at various concentrations. The phytochemical components of the plant extracts are probably responsible for the antimicrobial activity of the gel formulations. The 5% Aloe vera-Allium cepa (1 : 1) combination gel formulation showed excellent activity against Staphylococcus epidermidis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and Candida albicans, with MICs of 12.50, 25.00, 6.25, 25.00, and 12.50 mg/mL, respectively. The gels generally had good physicochemical and antimicrobial properties and could be used as antiacne remedies.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Formulation and Evaluation of Herbal‐Based Antiacne Gel Preparations

Ansong,

Asante,

Johnson

et al. 2023

BioMed Research International

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Formulation and Evaluation of Polyherbal-Spirulina Based Conditioning and Antioxidant Shampoo

2023

RJPT

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Herbal shampoos are cosmetics made up of traditional ayurvedic herbs used for cleaning the hair, and scalp as that regular shampoo. The aim of the present study is to formulate a polyherbal-spirulina based conditioning and antioxidant shampoo and to assess its physiochemical function that emphasizes safety, efficacy, elimination of harmful chemical ingredients, and substitution with safe natural ingredients in different proportions. Evaluation of physicochemical properties, antioxidant activity, and toxicity analysis of herbal and spirulina based shampoo done based on parameters of physicochemical properties such as visual inspection, pH, wetting time, % of solid contents, foam volume, and stability, dirt dispersion, and conditioning performance was performed. The formulated shampoo was clear, attractive, and appealing. It showed good cleansing and detergency, good foam stability, and excellent conditioning performance.

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Development and Characterization of Polyherbal Anti-acne face gel using Liquorice and Palash extract

N. Vaja,

H. Borkhataria,

S. Popaniya

2023

RJPT

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Anti-acne herbal formulations are used to treat acne vulgaris and also have the added benefit of not having any side effects, unlike synthetic medications. Acne is a bacterial-induced inflammatory skin disease caused by blockages in the pilosebaceous and inflammation. Antibiotics, both topical and systemic, are always used to treat acne, however antibiotic resistance can impair the success rate of acne treatment. The creation of effective therapeutic medicines relies heavily on medicinal plants. So, natural medicines are more acceptable because they are believed to be safer and have fewer adverse effects than manufactured ones. In the global market, herbal formulations are in high demand. The goal of this study is to produce and characterise herbal anti-acne face gel that contains neem (Azdirachta indica) extract, liquorice root (Glycyrrhiza glabra) extract, orange peel (Citrus aurantium var. sinensis) extract, and palash (Butea monosperma) flower extract. Although there are a variety of topical herbal formulations for acne on the market, we recommend creating a polyherbal formulation using a variety of herbal and synthetic ingredients. The plant has been found to have antimicrobial and anti-inflammatory properties in the literature. The prepared extract was screened to identify the presence or absence of various active principles like phenolic compounds, carbohydrates, flavanoids, glycosides, saponins, alkaloids, protein and amino acid. Polymers in various proportions were used to create several formulations ranging from F1 to F8. Colour, appearance, consistency, washability, pH, and spreadability and stability of prepared formulations (F1 to F8) were all examined.

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Formulation and Evaluation of Polyherbal Anti-Acne Gel

Cited by 3 publications

References 0 publications

Formulation and Evaluation of Herbal‐Based Antiacne Gel Preparations

Formulation and Evaluation of Herbal‐Based Antiacne Gel Preparations

Formulation and Evaluation of Polyherbal-Spirulina Based Conditioning and Antioxidant Shampoo

Development and Characterization of Polyherbal Anti-acne face gel using Liquorice and Palash extract

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