“…The cumulative drug release was calculated every 30 min for 2, 4, 6, 8, 10, 12, 24, 48, 72, 96, 120, 144, 168, and 192 h, respectively. The loading efficiency in the aqueous medium and cumulative release in percentage were calculated in triplicate using the formula mentioned below drug 0.25em loading 0.25em efficiency 0.25em ( % ) = initial 0.25em conc − final 0.25em conc initial 0.25em conc × 100 % …”