“…While there have been a couple of review papers in recent years concerning the basic principles of FO [21][22][23][24], draw solutions [22,[25][26][27][28][29][30][31], applications [21,25,27,[32][33][34][35][36][37][38][39], (bio)fouling [22,25,26,30,[40][41][42][43][44][45][46], membrane fabrication [19,23,30,35,39,43,47,48], or upscaling [49,50], we, for the major part of this review, discuss the challenges of FO evidences from various literatures to prove the unreliability of the existing structural parameter approaches. In addition, we will highlight that, beyond a certain water permeability, the true bottleneck is the mechanical support of the membrane instead of the selective membrane layer.…”