2016
DOI: 10.3109/14767058.2015.1135120
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Four Hours is Enough for Lactation Interruption After High-Dose Methylprednisolone Treatment in Multiple Sclerosis Mothers by Measuring Milk Cortisol Levels

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“…Transfer of high doses of IV CS into the breast milk is very low (about 1% of the maternal amount). 133,134 The peak is observed 1 hour after the infusion. The half-life in the breast milk is 2 hours; there is, therefore, no accumulation in case of repeated administration over several days.…”
Section: Resultsmentioning
confidence: 98%
“…Transfer of high doses of IV CS into the breast milk is very low (about 1% of the maternal amount). 133,134 The peak is observed 1 hour after the infusion. The half-life in the breast milk is 2 hours; there is, therefore, no accumulation in case of repeated administration over several days.…”
Section: Resultsmentioning
confidence: 98%
“…Transfer of high doses of IV CS into the breastmilk is very low (about 1% of the maternal amount). 55,56 The peak is observed 1 hour after the infusion. The half-life of the breastmilk is 2 hours; there is, therefore, no accumulation in case of repeated administration over several days.…”
Section: Resultsmentioning
confidence: 98%