Four Hydatid Cysts in One Family: Is Family Screening Necessary?

Abstract

ÖZKist hidatik çoğunlukla Echinococcus granulosusun neden olduğu paraziter kistik bir hastalıktır. Enfekte köpekten bulaşan parazit, hayvancılığın yaygın olduğu bölgelerde daha yaygın görülmektedir. Bulantı, kusma ve ateş yakınmaları ile başvuran 10 yaşındaki ilk olgunun muayenesinde sağ akciğerde solunum sesleri azalmış ve krepitan ralleri bulunmaktaydı. Hepatomegali saptanan hastanın, radyolojik görün-tülemelerinde akciğer ve karaciğerinde kist saptandı. Hastanın kist hidatik tanısının serolojik olarak da doğrulanması ardından rezeksiyon ve albendazol tedavisi verildi. Hastanın aile taramasında semptomsuz olan 6 yaşındaki erkek kardeşinde karaciğer ve dalakta; aralıklı karın ağrıları olan 33 yaşındaki annesinde akciğer, karaciğer, dalak ve sağ böbrekte ve 33 yaşındaki semptomsuz babasının karaciğer ve sol böb-reğinde kistlerin görülmesi ardından kist hidatik tanıları serolojik olarak doğrulandı. Hastalara rezeksiyon ve albendazol tedavileri uygulandı. Bu makalede aynı aileden hidatik kist tanısı alan dört birey sunularak; özellikle hayvancılığın yaygın olduğu, hastalık için endemik olan böl-gelerde aile taramasının önemi vurgulanmak istendi. (Turkiye Parazitol Derg 2015; 39: 319-22) Anahtar Kelimeler: Kist hidatik, aile taraması, hayvancılık Geliş Tarihi: 18.05.2015Kabul Tarihi: 14.11.2015 ABSTRACTHydatid cyst is a parasitic infection mostly caused by Echinococcus granulosus. As transmission occurs from infected dogs, it is endemic in animal husbandry regions. Here four patients within the same family are presented. The first patient is a 10 year-old girl admitted with nausea, vomiting, and fever. On her physical examination, there were decreased respiratory sounds in the right lung, rales, and hepatomegaly. In the radiological examination, cysts were seen in both her lung and liver. After the confirmation of the diagnosis with a serological examination, surgical resection was performed, and albendazole treatment was given. On family screening, cysts were detected in the liver and spleen in her asymptomatic 6-year-old brother; in the lung, liver, spleen, and right kidney in her 33-year-old mother who had repeating abdominal pain; and in the liver and left kidney in her 33-year-old asymptomatic father. Hydatid cyst infection was serologically confirmed in all patients, and they were given albendazole and were surgically treated. In this case report, four patients in the same family and diagnosed as having hydatid cysts were presented. It was emphasized that once a hydatid cyst was diagnosed, family screening became important, in endemic regions in particular. (Turkiye Parazitol Derg 2015; 39: 319-22)

Kistik Ekinokokkoz Ön Tanısı ile Başvuran Hastaların Radyolojik, Hemogram ve Biyokimyasal Analizlerinin Değerlendirilmesi

“…Akgün et al, [17] reported that cyst formation was detected radiologically in 100 of 163 cases studied in their research, 70% of the cases had liver, 25% lung, and 5% other organ involvement. Karadagli et al, [18] reported that it was possible to observe the disease more commonly in individuals who share the same environment and consume similar foods, considering the disease's mode of transmission. The educational backgrounds, living environments, occupations, hobbies and socioeconomic statuses of individuals in a society affect their risk of being infected by E. granulosus.…”

Intrathoracic multiple recurrence and bilateral endobronchial rupture of cyst hydatid disease; the rare cause of anaphylaxis

“…It is seen as endemic in regions such as Middle Eastern countries where animal breeding is common like eastern part of our country. There are also reports in the literature suggesting that family screening should be performed, especially when a newly diagnosed patient is identified in endemic areas [2] .…”

Prevalence of cystic echinococcosis in relatives of patients undergoing surgery for hepatic cystic echinococcosis in an endemic region

“…It is noteworthy that the transmission of the definitive host to humans occurs via the fecal-oral route and no reports have ever found genetic traits that predispose to the infection [ 9 ]. Nonetheless, transmission within family groups is seldom addressed in the literature, with scarce reports such as those by Musio, who documented EQ infection in seven out of 11 members of an Athenian family in Greece [ 9 ]; Karadağlı, reporting CE in four family members [ 10 ]; Yang, who observed a prevalence of 9% for CE and 5.9% for alveolar echinococcosis (a combined prevalence of 14.9%) among individuals from Nanwan, Ningxia Hui, China. This study involved an Islamic community comprising 167 members across four families, wherein 12 family members died to CE [ 11 ]; and Larrieu in a case-control study of the risk factors for CE among children in Rio Negro, Argentina, founded that the main risk factor significantly associated with CE were having a family member with the disease (OR = 3.11; CI = 0.92–10.47) [ 12 ].…”